ArticleBioinformatics (Oxford, England)2023
StarPep Toolbox: an open-source software to assist chemical space analysis of bioactive peptides and their functions using complex networks.
Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Complex Networks in Bioactive Peptide Research: A Methodological Review.Biomolecules · 2026Review
- Generative AI for controllable protein sequence design: A survey.npj drug discovery · 2026Review
- A 2026 Update on Computational Approaches to the Discovery and Design of Antimicrobial Peptides.Antibiotics (Basel, Switzerland) · 2026Article
- Leveraging Different Distance Functions to Predict Antiviral Peptides with Geometric Deep Learning from ESMFold-Predicted Tertiary Structures.Antibiotics (Basel, Switzerland) · 2026Article
- AI-driven antimicrobial peptide characterization unveils novel motifs for drug design.Scientific reports · 2025Article
- Mapping the Antibiofilm Peptide Space with Similarity Networks and Curated Negative Sets.ACS omega · 2025Article
- Half-Space Proximal Networks (HSPNs): A Proxy for Multi-Query Similarity Searching Models Predicting Tumor-Homing Peptides.ACS omega · 2025Article
- Optimal Descriptor Subset Search via Chemical Information and Target Activity-Guided Algorithm for Antimicrobial Peptide Prediction.Journal of chemical information and modeling · 2025Article
- Unlocking Antimicrobial Peptides: In Silico Proteolysis and Artificial Intelligence-Driven Discovery from Cnidarian Omics.Molecules (Basel, Switzerland) · 2025Article
- Unveiling Encrypted Antimicrobial Peptides from Cephalopods' Salivary Glands: A Proteolysis-Driven Virtual Approach.ACS omega · 2024Article
- Peptide hemolytic activity analysis using visual data mining of similarity-based complex networks.NPJ systems biology and applications · 2024Article
- Innovative Alignment-Based Method for Antiviral Peptide Prediction.Antibiotics (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
motivationAntimicrobial peptides (AMPs) are promising molecules to treat infectious diseases caused by multi-drug resistance pathogens, some types of cancer, and other conditions. Computer-aided strategies are efficient tools for the high-throughput screening of AMPs.
resultsThis report highlights StarPep Toolbox, an open-source and user-friendly software to study the bioactive chemical space of AMPs using complex network-based representations, clustering, and similarity-searching models. The novelty of this research lies in the combination of network science and similarity-searching techniques, distinguishing it from conventional methods based on machine learning and other computational approaches. The network-based representation of the AMP chemical space presents promising opportunities for peptide drug repurposing, development, and optimization. This approach could serve as a baseline for the discovery of a new generation of therapeutics peptides. AVAILABILITY AND IMPLEMENTATION: All underlying code and installation files are accessible through GitHub (https://github.com/Grupo-Medicina-Molecular-y-Traslacional/StarPep) under the Apache 2.0 license.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.