Evidence map›Paper›PMID 37603571›Full record

ArticlePloS one2023

Factors associated with Alzheimer's disease prevalence and mortality in Brazil-An ecological study.

Murilo Bastos, Michael Pereira da Silva, Danyele da Silva, Glauco Nonose Negrão, Graziele Schumanski, Weber Claudio Francisco Nunes da Silva, Juliana Sartori Bonini

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Murilo BastosLaboratório de Neurociência e Comportamento, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.ORCID 0000-0003-0358-8738
Michael Pereira da SilvaFaculty of Medicine, Federal University of Rio Grande, Rio Grande, RS, Brazil.
Danyele da SilvaDepartamento de Enfermagem, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.
Glauco Nonose NegrãoAssociação de Estudos, Pesquisa e Assistência as Pessoas com Doença de Alzheimer, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.
Graziele SchumanskiProfnit, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.ORCID 0000-0002-5619-7266
Weber Claudio Francisco Nunes da SilvaAssociação de Estudos, Pesquisa e Assistência as Pessoas com Doença de Alzheimer, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.ORCID 0000-0002-4688-3115
Juliana Sartori BoniniLaboratório de Neurociência e Comportamento, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A few epidemiological studies are evaluating the prevalence and mortality rates of Alzheimer's disease, with no one using a nationwide sample of Brazilian elderlies. This study aims to calculate the prevalence of Alzheimer's disease and investigate possible associations with sociodemographic and lifestyle factors and the presence of diseases non-communicable, and the prevalence and mortality for all Brazilian state capitals. This is an ecological design study made with secondary public data provided by the Ministry of Health. Prevalence rates were calculated based on the analysis of the dispensing of Alzheimer's disease-specific drugs. Correlation analyzes were performed between rates and factors, and a multiple linear regression analysis was used to analyze possible associations between variables, controlled for each other. AD prevalence was 313/100,000. Prevalence rates were positively associated with primary health care coverage factors and negatively associated with ultra-processed food consumption and physical activity levels. AD mortality was 98/100,000. Mortality rates were positively associated with the proportion of obese elderly and elderly living on up to half the minimum wage and were inversely associated with the proportion of elderly with diabetes factors. We found positive and negative associations of sociodemographic, behavioral and diabetes indicators with Alzheimer's disease prevalence and mortality, which provide data that can be investigated by studies with different designs.

Indexed as

Alzheimer DiseaseAgedBrazilFood, ProcessedHumansIncomePrevalence

Identifiers

PMID37603571
PMCPMC10441790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.