Evidence map›Paper›PMID 37603550›Full record

ArticlePLOS global public health2023

Six-month incidence of hypertension and diabetes among adults with HIV in Tanzania: A prospective cohort study.

Francis M Sakita, Paige O'Leary, Sainikitha Prattipati, Monica S Kessy, Kajiru G Kilonzo, Blandina T Mmbaga, Anzibert A Rugakingira, Preeti Manavalan, Nathan M Thielman, Dorothy Samuel and 1 more

Open access · goldAbstract read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Francis M SakitaKilimanjaro Christian Medical Center, Moshi, Tanzania.
Paige O'LearyDepartment of Emergency Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.ORCID https://orcid.org/0000-0003-3697-5953
Sainikitha PrattipatiDuke Global Health Institute, Duke University, Durham, North Carolina, United States of America.ORCID https://orcid.org/0000-0003-4470-6120
Monica S KessyBenjamin Mkapa Hospital, Dodoma, Tanzania.
Kajiru G KilonzoKilimanjaro Christian Medical Center, Moshi, Tanzania.ORCID https://orcid.org/0000-0002-0367-5826
Blandina T MmbagaKilimanjaro Christian Medical Center, Moshi, Tanzania.ORCID https://orcid.org/0000-0002-5550-1916
Anzibert A RugakingiraMinistry of Health, Dodoma, Republic of Tanzania.
Preeti ManavalanDuke Global Health Institute, Duke University, Durham, North Carolina, United States of America.ORCID https://orcid.org/0000-0001-7587-224X
Nathan M ThielmanDuke Global Health Institute, Duke University, Durham, North Carolina, United States of America.ORCID https://orcid.org/0000-0001-8152-2879
Dorothy SamuelDepartment of Emergency Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.
Julian T HertzDepartment of Emergency Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.ORCID https://orcid.org/0000-0002-7396-4789
Duke University · USKilimanjaro Christian Medical Centre · TZMinistry of Health, Community Development, Gender, Elderly and Children · TZTanzania National Parks · TZ

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
NIAID NIH HHS P30 AI064518
6 · The paper itself

Abstract

Data describing the incidence of hypertension and diabetes among people with HIV in sub-Saharan Africa remain sparse. In this study, adults with HIV were enrolled from a public clinic in Moshi, Tanzania (September 2020-March 2021). At enrollment, a survey was administered to collect information on comorbidities and medication use. Each participant's blood pressure and point-of-care glucose were measured. Baseline hypertension was defined by blood pressure ≥140/90 mmHg or self-reported hypertension at enrollment. Baseline diabetes was defined by self-reported diabetes or hyperglycemia (fasting glucose ≥126 mg/dl or random glucose ≥200 mg/dl) at enrollment. At 6-month follow-up, participants' blood pressure and point-of-care glucose were again measured. Incident hypertension was defined by self-report of new hypertension diagnosis or blood pressure ≥140/90 mmHg at follow-up in a participant without baseline hypertension. Incident diabetes was defined as self-report of new diabetes diagnosis or measured hyperglycemia at follow-up in a participant without baseline diabetes. During the study period, 477 participants were enrolled, of whom 310 did not have baseline hypertension and 457 did not have baseline diabetes. At six-month follow-up, 51 participants (95% CI: 38, 67) had new-onset hypertension, corresponding to an incidence of 33 new cases of hypertension per 100 person-years. Participants with incident hypertension at 6-month follow-up were more likely to have a history of alcohol use (90.2% vs. 73.7%, OR = 3.18, 95% CI:1.32-9.62, p = 0.008) and were older (mean age = 46.5 vs. 42.3, p = 0.027). At six-month follow-up, 8 participants (95% CI: 3, 16) had new-onset diabetes, corresponding to an incidence of 3 new cases of diabetes per 100 person-years. In conclusion, the incidence of elevated blood pressure and diabetes among Tanzanians with HIV is higher than what has been reported in high-income settings.

Identifiers

PMID37603550
PMCPMC10441788
OpenAlexW4386023055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.