ArticleMedical physics2023
Exploration of the pulse pileup effects in a clinical CdTe-based photon-counting computed tomography.
Article in Medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- High-Speed Detection of X-ray Pulses Using a Digital Counter Coupled with Perovskite Composite Scintillators.ACS applied materials & interfaces · 2026Article
- Development of a customizable model for spectral photon-counting detector CT.Medical physics · 2025Article
- User evaluation of detector performance in clinical photon-counting and energy-integrating CT scanners using DICOM images.Medical physics · 2025Article
- Three-dimensional noise characteristics of clinical photon counting detector CT.Medical physics · 2025Article
- Simulating and correcting the pileup effect in deep-silicon photon-counting CT.Medical physics · 2025Article
- Iodine quantification performance with deep silicon-based Photon-Counting CT: A virtual imaging trial study.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025Article
- In silico modeling of a clinical photon-counting CT system: Verification and validation.Medical physics · 2025Article
- Quantifying photon counting detector (PCD) performance using PCD-CT images.Medical physics · 2025Article
- Performance of iodine quantification through high-pitch dual-source photon-counting CT: a phantom study.Japanese journal of radiology · 2025Article
- Quantitative Accuracy of CT Protocols for Cross-sectional and Longitudinal Assessment of COPD: A Virtual Imaging Study.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- Contrast-to-noise ratio comparison between X-ray fluorescence emission tomography and computed tomography.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- A framework to model charge sharing and pulse pileup for virtual imaging trials of photon-counting CT.Physics in medicine and biology · 2024Article
- Chances and challenges of photon-counting CT in musculoskeletal imaging.Skeletal radiology · 2024Review
- Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints.Current osteoporosis reports · 2024Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHigh tube current generates a high flux of x-rays to photon counting detectors (PCDs) that can potentially result in the piling up of pulses formed by concurrent photons, which can cause count loss and energy resolution degradation. PURPOSE: To evaluate the performance of clinical photon-counting CT (PCCT) systems in high flux, potentially influenced by pulse pileup effects, in terms of task-generic image quality metrics.
methodsA clinical phantom was scanned on a commercial PCCT scanner (NAEOTOM Alpha, Siemens) at 120 kV under fourteen different tube current levels (40-1000 mA) with a rotation time of 0.25 s and a pitch of 1. The dose levels corresponded to CTDI
resultsThe 50% cut-off frequency of TTF (f
conclusionsIncreasing tube currents did not affect the spatial resolution, but slightly affected the CT number and noise measurements of the clinical PCCT system. However, the effects were only considerable at clinically irrelevant tube currents used on a small 20-cm phantom. In general clinical practices, automatic exposure control techniques are used to decrease the variation of flux on the detector, which alleviates the chances of detector saturation due to high count rates. The observed effects could be due to pulse pileup, signal-dependent filtration of the system, or nonlinearities in the reconstruction algorithm. In conclusion, either the deadtime of the detector used in the photon-counting CT system is shorter such that count losses due to pulse pileup are negligible, or pulse pileup has inconsiderable effects on the image quality of clinical photon-counting CT systems in routine clinical practice due to possible corrections applied on the system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.