Evidence map›Paper›PMID 37602567›Full record

ArticleAutism research : official journal of the International Society for Autism Research2023

Paisley: Preliminary validation of a novel app-based e-Screener for ASD in children 18-36 months.

Makayla G Honaker, Amy S Weitlauf, Amy R Swanson, Madison Hooper, Nilanjan Sarkar, Joshua Wade, Zachary E Warren

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Makayla G HonakerDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-6072-3759
Amy S WeitlaufDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Amy R SwansonVanderbilt Kennedy Center, Treatment and Research Institute for Autism Spectrum Disorders (TRIAD), Nashville, Tennessee, USA.
Madison HooperDepartment of Psychology, Vanderbilt University, Nashville, Tennessee, USA.
Nilanjan SarkarAdaptive Technology Consulting, Nashville, Tennessee, USA.
Joshua WadeAdaptive Technology Consulting, Nashville, Tennessee, USA.
Zachary E WarrenDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Autoscreen: An innovative e-health solution for early identification of Autism Spectrum Disorder Phase IIR44MH115528 · NIMH · ADAPTIVE TECHNOLOGY CONSULTING, LLC · PI WADE, JOSHUA W · 2019 to 2020
$1.0M
Autoscreen: An innovative e-health solution for early identification of autism spectrum disorderR43MH115528 · NIMH · ADAPTIVE TECHNOLOGY CONSULTING, LLC · PI WADE, JOSHUA W · 2018 to 2018
$225k
NCATS NIH HHS UL1 TR002243NICHD NIH HHS P50 HD103537NIH HHSNIMH NIH HHS R43 MH115528NIMH NIH HHS R44 MH115528
6 · The paper itself

Abstract

The purpose of this study was to assess the validity of an autism e-screener, Paisley, when utilized in a clinical research setting via a tablet application. The Paisley application used a series of play-based activities, all of which incorporated varying aspects of the ASD-PEDS. Participants included children (18-36 months; n = 198) referred for evaluation of autism spectrum disorder (ASD) and community providers (n = 66) with differing levels of familiarity with ASD. Community providers administered the Paisley application to children who then completed a comprehensive psychological evaluation. Based on comprehensive evaluation, 75% of children met diagnostic criteria for ASD. Paisley scores were significantly higher for children diagnosed with ASD (15.06) versus those not diagnosed (9.34). The newly determined cutoff ASD-PEDS cutoff score of 13 had significantly higher specificity and positive predictive value than the originally proposed cutoff of 11. Results support the use of Paisley by community providers to identify autism risk in toddlers. Limitations and strengths of the work, as well as opportunities for future clinical validation, are described.

Indexed as

Autism Spectrum DisorderAutistic DisorderMobile ApplicationsHumansPredictive Value of Testsautism spectrum disorderclinicalearly identificatione-screenerpaisley projectresearch

Identifiers

PMID37602567
PMCPMC10857772

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.