Evidence map›Paper›PMID 37602439›Full record

ArticleThe Journal of international medical research2023

Clinical significance of serum S100 calcium-binding protein A12 concentrations in patients with community-acquired pneumonia.

Haoling Wang, Dongqiong Li, Youli Wang, Guangjian Mao, Guozhou Lu, Qiqin Lan, Lianchun Xiao, Wenjuan Tang, Yiqi Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Haoling WangDepartment of Respiratory and Critical Care Medicine, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Dongqiong LiDepartment of Respiratory and Critical Care Medicine, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Youli WangDepartment of Respiratory and Critical Care Medicine, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Guangjian MaoDepartment of Respiratory and Critical Care Medicine, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Guozhou LuDepartment of Pharmacy, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Qiqin LanDepartment of Anesthesiology, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Lianchun XiaoDepartment of Respiratory and Critical Care Medicine, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Wenjuan TangDepartment of Laboratory, Xichang People's Hospital, Xichang City, Sichuan Province, China.
Yiqi LiuDepartment of Respiratory and Critical Care Medicine, Xichang People's Hospital, Xichang City, Sichuan Province, China.ORCID 0009-0006-7331-7959
Xichang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the clinical significance of serum S100 calcium-binding protein A12 (S100A12) concentrations in patients with community-acquired pneumonia (CAP).

methodsThis was a case-control study. We selected 120 patients with CAP treated in Xichang People's Hospital from January to June 2022 as the case group. Sixty healthy adults without a history of basic diseases were selected as the control group. The patients in the case group were divided into the low S100A12 and high S100A12 subgroups. Serum S100A12, C-reactive protein (CRP), and procalcitonin (PCT) concentrations, the leukocyte count, and other study parameters were compared.

resultsSerum S100A12, CRP, and PCT concentrations and the leukocyte count were higher in the case group than in the control group. The baseline confusion, urea, respiratory rate, blood pressure, and age ≥ 65 score, baseline pneumonia severity index score, and 30-day mortality rate were higher in the high S100A12 subgroup than in the low S100A12 subgroup. Serum CRP and PCT concentrations and the leukocyte count were higher in the high S100A12 subgroup than in the low S100A12 subgroup.

conclusionPatients with high serum S100A12 concentrations have more severe CAP, a more serious inflammatory reaction, and higher 30-day mortality.

Indexed as

Community-Acquired InfectionsPneumoniaAdultCase-Control StudiesClinical RelevanceC-Reactive ProteinHumansInflammationProcalcitoninS100A12 ProteinC-Reactive ProteinProcalcitoninS100A12 ProteinCommunity-acquired pneumoniaC-reactive proteinleukocytemortalityprocalcitoninS100 calcium-binding protein A12 (S100A12)

Identifiers

PMID37602439
PMCPMC10467374
OpenAlexW4386020256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.