Evidence map›Paper›PMID 37602382›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2023

Treatment with gut-specific nonsteroidal anti-inflammatory drug attenuates metabolic inflammation but not body mass in fattening ground squirrels.

Jewel Zur Tulod, Nathan D Witman, Kirsten Grond, Khrystyne N Duddleston, Courtney C Kurtz

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jewel Zur TulodDepartment of Biology, University of Wisconsin Oshkosh, Oshkosh, Wisconsin, United States.
Nathan D WitmanDepartment of Biology, University of Wisconsin Oshkosh, Oshkosh, Wisconsin, United States.
Kirsten GrondDepartment of Biological Sciences, University of Alaska Anchorage, Anchorage, Alaska, United States.ORCID 0000-0001-6197-7139
Khrystyne N DuddlestonDepartment of Biological Sciences, University of Alaska Anchorage, Anchorage, Alaska, United States.
Courtney C KurtzDepartment of Biology, University of Wisconsin Oshkosh, Oshkosh, Wisconsin, United States.ORCID 0000-0001-5408-8544
University of Wisconsin–Oshkosh · USUniversity of Alaska Anchorage · US

Funding

Renovation of LARS for Arctic Ground Squirrel BreedingP20GM130443 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI Kriya L Dunlap · 2019 to 2026
$16.4M
Microbiota and Inflammation in Adiposity: The Ground Squirrel ModelR15GM124586 · NIGMS · UNIVERSITY OF WISCONSIN OSHKOSH · PI KURTZ, COURTNEY C · 2018 to 2022
$834k
NIGMS NIH HHS P20 GM130443NIGMS NIH HHS R15 GM124586
6 · The paper itself

Abstract

The active season of hibernators corresponds to rapid adiposity in preparation for the next hibernation season. We have previously shown that this dramatic increase in adipose mass is associated with metabolic inflammation similar to what is seen in obesity and metabolic disease. We next sought to determine whether curbing this inflammation at its source (i.e., the gut) would attenuate weight gain in fattening 13-lined ground squirrels (

Indexed as

AdiposityAnti-Inflammatory Agents, Non-SteroidalInflammationSciuridaeAdipose Tissue, WhiteAnimalsCytokinesFemaleGastrointestinal MicrobiomeHibernationMaleMesalamineWeight GainAnti-Inflammatory Agents, Non-SteroidalCytokinesMesalamineadipose tissuehibernatorIL-6mesalazineTNF-α

Identifiers

PMID37602382
PMCPMC11178295
OpenAlexW4386019572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.