Evidence map›Paper›PMID 37602348›Full record

ArticleInternational journal of ophthalmology2023

Clinical and genetic characteristics of retinoblastoma patients in a single center with four novel

Özge Vural, Hatice Tuba Atalay, Gulsum Kayhan, Bercin Tarlan, Merve Oral, Arzu Okur, Faruk Güçlü Pınarlı, Ceyda Karadeniz

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Özge VuralDepartment of Pediatric Hematology and Oncology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Hatice Tuba AtalayDepartment of Ophthalmology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Gulsum KayhanDepartment of Medical Genetics, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Bercin TarlanDepartment of Ophthalmology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Merve OralDepartment of Ophthalmology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Arzu OkurDepartment of Pediatric Hematology and Oncology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Faruk Güçlü PınarlıDepartment of Pediatric Hematology and Oncology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Ceyda KaradenizDepartment of Pediatric Hematology and Oncology, Gazi University Faculty of Medicine, Ankara 06500, Türkiye.
Gazi University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the clinical and genetic characteristics of children diagnosed with retinoblastoma (RB) at Gazi University Faculty of Medicine's Department of Pediatric Oncology.

methodsAll cases diagnosed with RB and received treatment and follow-up in the Ophthalmology and Pediatric Oncology Department, October 2016 to May 2021 were evaluated retrospectively. The

resultsThis study included 53 cases with 67 RB-affected eyes during the study period. The mean age was 24.6 (median: 18.5, range: 3-151)mo. There were 15 (22.3%) Group D eyes and 39 (58.2%) Group E eyes. The

conclusionFour novel variants are described and one of them is found in two different patients. This data is crucial for assessing prognosis. It serves as a guide for estimating the long-term risk of secondary malignancy as well as the short-term risk of developing additional malignancies in the same eye and the other eye.

Indexed as

next generation sequencingRB1 novel mutationsretinoblastoma

Identifiers

PMID37602348
PMCPMC10398531
OpenAlexW4385260071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.