Evidence map›Paper›PMID 37602238›Full record

ArticleFrontiers in neurology2023

Semantic intrusion errors are associated with plasma Ptau-181 among persons with amnestic mild cognitive impairment who are amyloid positive.

Rosie E Curiel Cid, Alexandra Ortega, Elizabeth A Crocco, Diana Hincapie, Karen N McFarland, Ranjan Duara, David Vaillancourt, Steven T DeKosky, Glenn Smith, Efrosyni Sfakianaki and 6 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Cognitive dysfunction in women with theJournal of Alzheimer's disease : JAD · 2026
    Article
  3. Article
  4. Article
  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rosie E Curiel CidCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Alexandra OrtegaCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Elizabeth A CroccoCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Diana HincapieCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Karen N McFarlandDepartment of Neurology and the Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, United States.
Ranjan DuaraDepartment of Neurology and the Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, United States.
David VaillancourtDepartment of Applied Physiology and Kinesiology, Gainesville, FL, United States.
Steven T DeKoskyDepartment of Neurology and McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Glenn SmithDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL, United States.
Efrosyni SfakianakiCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Monica RosselliDepartment of Psychology, Florida Atlantic University, Boca Raton, FL, United States.
Warren W BarkerWien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami, FL, United States.
Malek AdjouadiCenter for Advanced Technology and Education, Florida International University, Miami, FL, United States.
Yarlenis BarretoCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Yuleidys FeitoCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
David A LoewensteinCenter for Cognitive Neuroscience and Aging, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Semantic intrusion errors (SI) have distinguished between those with amnestic Mild Cognitive Impairment (aMCI) who are amyloid positive (A+) versus negative (A-) on positron emission tomography (PET). Method: This study examines the association between SI and plasma - based biomarkers. One hundred and twenty-eight participants received SiMoA derived measures of plasma pTau-181, ratio of two amyloid-β peptide fragments (Aβ42/Aβ40), Neurofilament Light protein (NfL), Glial Fibrillary Acidic Protein (GFAP), ApoE genotyping, and amyloid PET imaging. Results: The aMCI A+ ( Discussion: A combination of plasma biomarkers, ApoE positivity and SI had high specificity in identifying A+ from A- aMCI cases.

Indexed as

ApoEinhibitory controlLASSI-Lmild cognitive impairmentplasma biomarkersp-tau amyloidsemantic intrusionssematic interference

Identifiers

PMID37602238
PMCPMC10436611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.