Evidence map›Paper›PMID 37602231›Full record

ArticleComputational and structural biotechnology journal2023

Synergetic effect of β-asarone and cannabidiol against Aβ aggregation

Fangyuan Duan, Ting Ju, Chen Song, Mengyao Liu, Yi Xiong, Xue Han, Weihong Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fangyuan DuanSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Ting JuSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Chen SongSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Mengyao LiuSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Yi XiongSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Xue HanSchool of Medicine and Health, Harbin Institute of Technology, Harbin 150001, China.
Weihong LuSchool of Medicine and Health, Harbin Institute of Technology, Harbin 150001, China.
Harbin Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, and it is unlikely that any single drug or intervention will be very successful. The pathophysiology of Alzheimer's disease involves a range of complicated biological processes, including the accumulation of beta-amyloid protein and tau protein. Given the complexity of AD and amyloid accumulation, a combination of interventions remains to be further explored. Here, we investigated the potential of combining β-asarone and cannabidiol (CBD) as a treatment for AD. The study analyzed the combined effects of these two phytochemicals on beta-amyloid (Aβ) protein aggregation and toxicity in bulk solution, in cells as well as in

Indexed as

Alzheimer’s diseaseAmyloid βCBDC. elegansPhytochemicalsβ-asarone

Identifiers

PMID37602231
PMCPMC10432915
OpenAlexW4385336213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.