Evidence map›Paper›PMID 37601888›Full record

ArticleEJHaem2023

Administration of combined venetoclax and azacitidine in a patient with acute myeloid leukemia and multiple comorbidities undergoing dialysis: A case report.

Yuina Akagi, Yusuke Yamashita, Hideki Kosako, Yoshiaki Furuya, Hiroki Hosoi, Toshiki Mushino, Shogo Murata, Akinori Nishikawa, Shinobu Tamura, Taisei Nakao and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in EJHaem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yuina AkagiDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.
Yusuke YamashitaDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.ORCID https://orcid.org/0000-0002-9133-8183
Hideki KosakoDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.
Yoshiaki FuruyaDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.
Hiroki HosoiDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.
Toshiki MushinoDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.ORCID https://orcid.org/0000-0001-7700-5262
Shogo MurataDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.
Akinori NishikawaDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.
Shinobu TamuraDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.ORCID https://orcid.org/0000-0002-1150-0970
Taisei NakaoDepartment of Hematology Naga Municipal Hospital Wakayama Japan.
Takashi SonokiDepartment of Hematology/Oncology Wakayama Medical University Wakayama Japan.ORCID https://orcid.org/0000-0002-0211-3311
Wakayama Medical University · JPNaga Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with acute myeloid leukemia (AML) who have comorbidities have limited treatment options, thereby resulting in poor prognosis. Venetoclax, a specific B-cell lymphoma-2 inhibitor, has recently been approved for AML in combination with hypomethylating agents; however, only one report has described its use in patients undergoing dialysis. Herein, we report the effectiveness of combined venetoclax and azacitidine in a 73-year-old man with AML undergoing dialysis and who was ineligible for standard therapies. The safety of venetoclax and azacitidine in patients undergoing dialysis has been reported, and their combination may be a feasible option for patients with AML undergoing dialysis.

Indexed as

acute myeloid leukemiaazacitidinedialysisvenetoclax

Identifiers

PMID37601888
PMCPMC10435694
OpenAlexW4379646498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.