Evidence map›Paper›PMID 37601485›Full record

ArticleJournal of drug delivery science and technology2023

Formulation and evaluation of paclitaxel-loaded boronated chitosan/alginate nanoparticles as a mucoadhesive system for localized cervical cancer drug delivery.

Kolawole Oluwadamilola Miriam, Ifeanafor Adaora Rosemary, Ifade Wuraola Adebimpe, Akinleye Moshood Olusola, Patrojanasophon Prasopchai, Silva Boladale Olanrewaju, Osuntoki Akinniyi Adediran

Open access · greenAbstract read
In one paragraph

Article in Journal of drug delivery science and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kolawole Oluwadamilola MiriamDepartment of Pharmaceutics and Pharmaceutical Technology, University of Lagos, Lagos State, Nigeria.
Ifeanafor Adaora RosemaryDepartment of Pharmaceutics and Pharmaceutical Technology, University of Lagos, Lagos State, Nigeria.
Ifade Wuraola AdebimpeDepartment of Pharmaceutics and Pharmaceutical Technology, University of Lagos, Lagos State, Nigeria.
Akinleye Moshood OlusolaDepartment of Pharmaceutical Chemistry, University of Lagos, Lagos State, Nigeria.
Patrojanasophon PrasopchaiFaculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand.
Silva Boladale OlanrewajuDepartment of Pharmaceutics and Pharmaceutical Technology, University of Lagos, Lagos State, Nigeria.
Osuntoki Akinniyi AdediranDepartment of Biochemistry, College of Medicine, University of Lagos, Lagos State, Nigeria.
University of Lagos · NGSilpakorn University · TH

Funding

Building Research And Innovation in Nigeria's Science - (BRAINS)D43TW010134 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF LAGOS · PI OGUNSOLA, FOLASADE TOLULOPE · 2015 to 2020
$3.2M
FIC NIH HHS D43 TW010134
6 · The paper itself

Abstract

Cervical cancer remains a significant global health challenge, and there is a need for innovative drug delivery systems to improve the efficacy of anticancer drugs. In this study, we developed and evaluated boronated chitosan/alginate nanoparticles (BCHIALG NPs) as a localized mucoadhesive drug delivery system for cervical cancer. Boronated chitosan (BCHI) was synthesized by incorporating 4-carboxyphenylboronic acid onto chitosan (CHI), and boronated chitosan/alginate nanoparticles (BCHIALG NPs) with varying polymer ratios were prepared using an ionic gelation method. The physical properties, drug loading capacity/encapsulation efficiency, mucoadhesive properties, and

Indexed as

alginateBoronated chitosancervical drug deliverynanoparticlespaclitaxeltransmucosal

Identifiers

PMID37601485
PMCPMC10434836
OpenAlexW4385507416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.