Evidence map›Paper›PMID 37601041›Full record

ArticleFrontiers in pharmacology2023

A phase 1 study of dimdazenil to evaluate the pharmacokinetics, food effect and safety in Chinese healthy subjects.

Fei Wang, Jingjing He, Yanling Zhou, Lijun Ye, Bei Li, Zhiyuan Ma, Chunyan Chen, Ruoxi Zhang, Zhaocun Lin, Jinshan Tang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Dimdazenil for the treatment of insomnia: a systematic review and narrative synthesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Fei WangPhase 1 Clinical Trial Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jingjing HeShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Yanling ZhouShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Lijun YePhase 1 Clinical Trial Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Bei LiPhase 1 Clinical Trial Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhiyuan MaPhase 1 Clinical Trial Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chunyan ChenShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Ruoxi ZhangShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Zhaocun LinShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Jinshan TangShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Zhiping JinZhejiang Jingxin Pharmaceutical Co., Ltd., Shaoxing, China.
Yu JiangShanghai Research Institute, Zhejiang Jingxin Pharmaceutical Co., Ltd., Shanghai, China.
Nengming LinPhase 1 Clinical Trial Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhejiang University · CNHangzhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dimdazenilGABAA receptorinsomniapartial positive allosteric agonistpharmacokineticssafety

Identifiers

PMID37601041
PMCPMC10432719
OpenAlexW4385461967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.