Evidence map›Paper›PMID 37600845›Full record

ArticleBioinformatics advances2023

Genesis-DB: a database for autonomous laboratory systems.

Gabriel K Reder, Alexander H Gower, Filip Kronström, Rushikesh Halle, Vinay Mahamuni, Amit Patel, Harshal Hayatnagarkar, Larisa N Soldatova, Ross D King

Abstract read
In one paragraph

Article in Bioinformatics advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. AutonoMS: Automated Ion Mobility Metabolomic Fingerprinting.Journal of the American Society for Mass Spectrometry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabriel K RederThe Department of Computer Science and Engineering, Chalmers University of Technology, Gothenburg, 412 58, Sweden.ORCID https://orcid.org/0000-0001-8918-0789
Alexander H GowerThe Department of Computer Science and Engineering, Chalmers University of Technology, Gothenburg, 412 58, Sweden.
Filip KronströmThe Department of Computer Science and Engineering, Chalmers University of Technology, Gothenburg, 412 58, Sweden.
Rushikesh HalleEngineering for Research (e4r™), Thoughtworks Technologies (India) Pvt Ltd, Pune, 411006, India.
Vinay MahamuniEngineering for Research (e4r™), Thoughtworks Technologies (India) Pvt Ltd, Pune, 411006, India.
Amit PatelEngineering for Research (e4r™), Thoughtworks Technologies (India) Pvt Ltd, Pune, 411006, India.
Harshal HayatnagarkarEngineering for Research (e4r™), Thoughtworks Technologies (India) Pvt Ltd, Pune, 411006, India.
Larisa N SoldatovaDepartment of Computing, Goldsmiths, University of London, London, SE14 6AD, United Kingdom.ORCID https://orcid.org/0000-0001-6489-3029
Ross D KingThe Department of Computer Science and Engineering, Chalmers University of Technology, Gothenburg, 412 58, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Summary: Artificial intelligence (AI)-driven laboratory automation-combining robotic labware and autonomous software agents-is a powerful trend in modern biology. We developed Genesis-DB, a database system designed to support AI-driven autonomous laboratories by providing software agents access to large quantities of structured domain information. In addition, we present a new ontology for modeling data and metadata from autonomously performed yeast microchemostat cultivations in the framework of the Genesis robot scientist system. We show an example of how Genesis-DB enables the research life cycle by modeling yeast gene regulation, guiding future hypotheses generation and design of experiments. Genesis-DB supports AI-driven discovery through automated reasoning and its design is portable, generic, and easily extensible to other AI-driven molecular biology laboratory data and beyond. Availability and implementation: Genesis-DB code and installation instructions are available at the GitHub repository https://github.com/TW-Genesis/genesis-database-system.git. The database use case demo code and data are also available through GitHub (https://github.com/TW-Genesis/genesis-database-demo.git). The ontology can be downloaded here: https://github.com/TW-Genesis/genesis-ontology/releases/download/v0.0.23/genesis.owl. The ontology term descriptions (including mappings to existing ontologies) and maintenance standard operating procedures can be found at: https://github.com/TW-Genesis/genesis-ontology.

Identifiers

PMID37600845
PMCPMC10432352

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.