Evidence map›Paper›PMID 37600714›Full record

ArticleFrontiers in endocrinology2023

Neuropilin 2 in osteoblasts regulates trabecular bone mass in male mice.

Lieve Verlinden, Stefanie Doms, Iris Janssens, Mark B Meyer, J Wesley Pike, Geert Carmeliet, Annemieke Verstuyf

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. A novel model to study the impact of gender-affirming therapy on bone in young male mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lieve VerlindenDepartment of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Stefanie DomsDepartment of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Iris JanssensDepartment of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Mark B MeyerDepartment of Nutritional Sciences, University of Wisconsin-Madision, Madison, WI, United States.
J Wesley PikeDepartment of Biochemistry, University of Wisconsin-Madision, Madison, WI, United States.
Geert CarmelietDepartment of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Annemieke VerstuyfDepartment of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Neuropilin 2 (NRP2) mediates the effects of class 3 semaphorins and vascular endothelial growth factor and is implicated in axonal guidance and angiogenesis. Moreover, NRP2 expression is suggested to be involved in the regulation of bone homeostasis. Indeed, osteoblasts and osteoclasts express NRP2 and male and female global Methods: We first examined the Results and discussion: We show that

Indexed as

Cancellous BoneNeuropilin-2OsteoblastsAnimalsCalcitriolCholecalciferolCross-Sectional StudiesFemaleMaleMiceVascular Endothelial Growth Factor ACalcitriolCholecalciferolNeuropilin-2Nrp2 protein, mouseVascular Endothelial Growth Factor Aboneneuropilin 2osteoblastosteoclastvitamin D

Identifiers

PMID37600714
PMCPMC10436209
OpenAlexW4385444565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.