Evidence map›Paper›PMID 37600507›Full record

ArticleMedComm2023

Discovery of deoxyandrographolide and its novel effect on vascular senescence by targeting HDAC1.

Zhongxiao Lin, Hao He, Yu Xian, Jianghong Cai, Qinyang Ge, Minghao Guo, Quan Zheng, Xiaoyan Liu, Chengke Mo, Xin Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. The histone deacetylase family in health and disease.Signal transduction and targeted therapy · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Zhongxiao LinState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Hao HeState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Yu XianState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Jianghong CaiState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Qinyang GeState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.ORCID https://orcid.org/0000-0002-8228-5235
Minghao GuoState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Quan ZhengState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Xiaoyan LiuState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Chengke MoGuangzhou Twelfth People's Hospital Guangzhou China.
Xin ZhangState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Wei QiState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Youming ZhangCAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China.
Lu LiangDepartment of Pharmacology Shanghai Key Laboratory of Bioactive Small Molecules School of Pharmacy Fudan University Shanghai China.
Xi-Yong YuGuangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology The NMPA and State Key Laboratory of Respiratory Disease School of Pharmaceutical Sciences and The Fifth Affiliated Hospital Guangzhou Medical University Guangzhou China.
Yi Zhun ZhuState Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy Macau University of Science and Technology Macau China.
Macau University of Science and Technology · MOChinese Academy of Sciences · CNFudan University · CNState Key Laboratory of Respiratory Disease · CNTwelfth Guangzhou City People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

deoxyandrographolideepigeneticFuziHDAC1network pharmacology

Identifiers

PMID37600507
PMCPMC10435835
OpenAlexW4386020342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.