Evidence map›Paper›PMID 37600420›Full record

ArticleHeliyon2023

Assessment of clinical characteristics and viral load in individuals infected by Delta and Omicron variants of SARS-CoV-2.

Sávio Luiz Pereira Nunes, Chirles Araújo de França, Gabriela Dias Rocha, Samily Aquino de Sá Oliveira, Mariana Ramos Freitas, Eliane Oliveira da Silva, Katia Sampaio Coutinho, Aline Silva Jerônimo, Gustavo Barbosa de Lima, Raul Emídio de Lima and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Sávio Luiz Pereira NunesPostgraduate Program in Applied Cellular and Molecular Biology, University of Pernambuco (UPE), Recife, Pernambuco, Brazil.
Chirles Araújo de FrançaMulti-User Research Laboratory (LAMUPE), Dr. Washington Antônio de Barros Hospital - EBSERH/UNIVASF, Petrolina, Pernambuco, Brazil.
Gabriela Dias RochaPostgraduate Program in Applied Cellular and Molecular Biology, University of Pernambuco (UPE), Recife, Pernambuco, Brazil.
Samily Aquino de Sá OliveiraMulti-User Research Laboratory (LAMUPE), Dr. Washington Antônio de Barros Hospital - EBSERH/UNIVASF, Petrolina, Pernambuco, Brazil.
Mariana Ramos FreitasMulti-User Research Laboratory (LAMUPE), Dr. Washington Antônio de Barros Hospital - EBSERH/UNIVASF, Petrolina, Pernambuco, Brazil.
Eliane Oliveira da SilvaVIII Regional Health Management, State Health Secretariat of Pernambuco, Petrolina, Pernambuco, Brazil.
Katia Sampaio CoutinhoVIII Regional Health Management, State Health Secretariat of Pernambuco, Petrolina, Pernambuco, Brazil.
Aline Silva JerônimoVIII Regional Health Management, State Health Secretariat of Pernambuco, Petrolina, Pernambuco, Brazil.
Gustavo Barbosa de LimaTechnology Platforms Center (NPT), Aggeu Magalhães Institute (IAM), FIOCRUZ-Pernambuco, Recife, Pernambuco, Brazil.
Raul Emídio de LimaTechnology Platforms Center (NPT), Aggeu Magalhães Institute (IAM), FIOCRUZ-Pernambuco, Recife, Pernambuco, Brazil.
Matheus Filgueira BezerraDepartament of Microbiology, Aggeu Magalhães Institute (IAM), FIOCRUZ-Pernambuco, Recife, Pernambuco, Brazil.
Filipe Zimmer DezordiDepartament of Entomology, Aggeu Magalhães Institute (IAM)- FIOCRUZ-Pernambuco, Recife, Pernambuco, Brazil.
Marcelo Henrique Santos PaivaDepartament of Entomology, Aggeu Magalhães Institute (IAM)- FIOCRUZ-Pernambuco, Recife, Pernambuco, Brazil.
Gabriel da Luz WallauDepartament of Entomology, Aggeu Magalhães Institute (IAM)- FIOCRUZ-Pernambuco, Recife, Pernambuco, Brazil.
Carlos Dornels Freire de SouzaCollegiate of Medicine, Federal University of the São Francisco Valley - UNIVASF, Petrolina, Pernambuco, Brazil.
Anderson da Costa ArmstrongCollegiate of Medicine, Federal University of the São Francisco Valley - UNIVASF, Petrolina, Pernambuco, Brazil.
Rodrigo Feliciano do CarmoPostgraduate Program in Applied Cellular and Molecular Biology, University of Pernambuco (UPE), Recife, Pernambuco, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In late 2021, a new variant of SARS-CoV-2 called Omicron emerged, replacing Delta worldwide. Although it has been associated with a lower risk of hospitalization and severe forms of COVID-19, there is little evidence of its relationship with specific symptoms and viral load. The aim of this study was to verify the relationship between Delta and Omicron variants of concern, viral load, and the occurrence of symptoms in individuals with COVID-19. Nasopharyngeal swab samples were collected and sequenced from patients with COVID-19 from the Northeast Region of Brazil between August 2021 and March 2022. The results showed a gradual replacement of the Delta variant by the Omicron variant during the study period. A total of 316 samples (157 Delta and 159 Omicron) were included. There was a higher prevalence of symptoms in Delta-infected individuals, such as coryza, olfactory and taste disturbances, headache, and myalgia. There was no association between viral load and the variants analyzed. The results reported here contribute to the understanding of the symptoms associated with the Delta and Omicron variants in individuals affected by COVID-19.

Indexed as

COVID-19DeltaOmicronSymptomsVariants of concernViral load

Identifiers

PMID37600420
PMCPMC10432967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.