Evidence map›Paper›PMID 37600080›Full record

ArticleApplied physics letters2023

Vortex-ultrasound for microbubble-mediated thrombolysis of retracted clots.

Howuk Kim, Bohua Zhang, Huaiyu Wu, Junjie Yao, Chengzhi Shi, Xiaoning Jiang

Open access · greenAbstract read
In one paragraph

Article in Applied physics letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Bohua ZhangDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, North Carolina 27695, USA.ORCID https://orcid.org/0000-0002-9329-0507
Huaiyu WuDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, North Carolina 27695, USA.ORCID https://orcid.org/0000-0003-2616-1171
Junjie YaoDepartment of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA.ORCID https://orcid.org/0000-0002-2381-706X
Xiaoning JiangDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, North Carolina 27695, USA.ORCID https://orcid.org/0000-0003-3605-3801
North Carolina State University · USDuke University · USGeorgia Institute of Technology · US

Funding

Integrated Dual-frequency Ultrasound Catheter for Accelerated Sonothrombolysis (iDUCAS)R01HL141967 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Xiaoning Jiang, Zhen Xu · 2018 to 2026
$4.1M
Photoacoustic-imaging-guided intravascular sonothrombolysisR21EB027304 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI JIANG, XIAONING, YAO, JUNJIE · 2019 to 2020
$411k
Dual Excitation Catheter-delivered Laser Ultrasound Thrombolysis (DECLUT) for Deep Vein Thrombosis (DVT) TreatmentR41HL154735 · NHLBI · SONOVASCULAR, INC. · PI JIANG, XIAONING · 2020 to 2020
$150k
NHLBI NIH HHS R01 HL141967NHLBI NIH HHS R41 HL154735NIBIB NIH HHS R21 EB027304
6 · The paper itself

Abstract

Endovascular sonothrombolysis has gained significant attention due to its benefits, including direct targeting of the thrombus with sonication and reduced side effects. However, the small aperture of endovascular transducers restricts the improvement of their potential clinical efficiency due to inefficient acoustic radiation. Hence, in an earlier study, we used vortex ultrasound with an endovascular ultrasound transducer to induce shear stress and enhance the clot lysis. In this study, the vortex acoustic transduction mechanism was investigated using numerical simulations and hydrophone tests. Following this characterization, we demonstrated the performance of the vortex ultrasound transducer in thrombolysis of retracted clots in

Identifiers

PMID37600080
PMCPMC10435273
OpenAlexW4385874155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.