Evidence map›Paper›PMID 37600015›Full record

ReviewFrontiers in neuroscience2023

Association between sedentary behavior and risk of cognitive decline or mild cognitive impairment among the elderly: a systematic review and meta-analysis.

Xiao-Ye Cai, Guo-Ping Qian, Feng Wang, Ming-Yang Zhang, Ying-Juan Da, Jing-Hong Liang

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Impact of Different Types of Sedentary Behaviour on Cognitive Function in Older Adults: A Systematic Review.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2026
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  16. Physical activity, neuropsychiatric symptoms, and physical function in nursing home residents: the HUNT 70+ study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Xiao-Ye CaiDepartment of Physical Education, Shanghai Normal University Tianhua College, Shanghai, China.
Guo-Ping QianFaculty of Physical Culture, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Feng WangDepartment of Physical Education, Shanghai Ocean University, Shanghai, China.
Ming-Yang ZhangFaculty of Physical Culture, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Ying-Juan DaDepartment of Physical Education, Shanghai Normal University Tianhua College, Shanghai, China.
Jing-Hong LiangDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Shanghai Normal University · CNChengdu Sport University · CNGdansk University of Physical Education and Sport · PLShanghai Ocean University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Existing evidence on the association between sedentary behavior (SB) and cognitive function remains inconclusive. Therefore, this study investigated the association between SB and the risk of cognitive decline (CD) or mild cognitive impairment (MCI) in the elderly. Methods: A comprehensive search was independently conducted by two researchers (XC and GQ) in seven electronic databases, including Medline (via PubMed), China Biology Medicine, Embase, Web of Science, China National Knowledge Infrastructure, Wanfang database, and VIP database for Chinese technical periodicals, covering studies published from the inception of database to June 2023. Studies that investigated the relationship between SB and the risk of CD or MCI in the elderly were included. The quality of the literature was assessed using the Newcastle-Ottawa Scale (NOS) and the Agency for Healthcare Research and Quality (AHRQ) assessment tools. The combined effect size analysis, subgroup analysis, and publication bias assessment were performed using STATA 14.0. Results: A total of 13 cross-sectional and 6 cohort studies involving 81,791 individuals were included, comprising 17 high-quality studies and 2 medium-quality studies. We found that SB was significantly associated with an increased risk of CD [odds ratio (OR) = 1.69, 95% confidence intervals (CI): 1.47-1.94] or MCI (OR = 1.34, 95% CI: 1.14-1.56) among the elderly. Subgroup analysis stratified according to comorbidity, lifestyle, family structure, publication year, and region showed statistical differences between groups, and the consistency of the results revealed the sources of the heterogeneity. Conclusion: This meta-analysis showed that SB is positively associated with the risk of CD or MCI in the elderly, providing a higher level of evidence for the promotion of healthy behaviors by clinicians and health policymakers. Due to the number and quality of the included articles, more high-quality longitudinal studies are needed to further confirm our findings.

Indexed as

cognitive declineelderlymeta-analysismild cognitive impairmentsedentary behavior

Identifiers

PMID37600015
PMCPMC10436513
OpenAlexW4385584088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.