Evidence map›Paper›PMID 37599532›Full record

ReviewJournal of Alzheimer's disease : JAD2023

Preventing Neurocognitive Decline in Adults Aging with HIV: Implications for Practice and Research.

Shameka L Cody, Gabe H Miller, Pariya L Fazeli, Ge Wang, Wei Li, Burel R Goodin, David E Vance

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of Alzheimer's disease : JAD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Neuro-HIV-New insights into pathogenesis and emerging therapeutic targets.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shameka L CodyCapstone College of Nursing, The University of Alabama, Tuscaloosa, AL, USA.
Gabe H MillerDepartment of Sociology, University of Alabama at Birmingham, Birmingham, AL, USA.
Pariya L FazeliSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Ge WangTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wei LiDepartment of Clinical and Diagnostic Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Burel R GoodinDepartment of Anesthesiology, Washington University Pain Center, Washington University, St. Louis, MO, USA.
David E VanceSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USHuazhong University of Science and Technology · CNUniversity of Alabama · USWashington University in St. Louis · US

Funding

Evaluation of Neurobiological Mechanisms Mediating the Effect of Immune Activation on Neurocognitive Impairment and the Role of Psychosocial Factors Among Women Living with HIVR01MH131177 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Andrea Norcini Pala, Pariya Fazeli Wheeler · 2022 to 2026
$3.3M
The Impact of Insomnia on Pain, Physical Function, and Inflammation in HIVR01HL147603 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOODIN, BUREL R., SORGE, ROBERT · 2019 to 2022
$2.8M
An RCT of Speed of Processing Training in Middle-Aged and Older Adults with HIVR01MH106366 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2016 to 2020
$2.6M
Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging with HIVR21AG076377 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WHEELER, PARIYA FAZELI · 2022 to 2023
$520k
Executive Function Training to Reduce Cognitive Intra-Individual Variability in Adults with HIVR21AG077957 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2022 to 2023
$408k
NHLBI NIH HHS R01 HL147603NIA NIH HHS L60 AG069338NIA NIH HHS R21 AG076377NIA NIH HHS R21 AG077957NIMH NIH HHS R01 MH106366NIMH NIH HHS R01 MH131177
6 · The paper itself

Abstract

Mild to moderate forms of neurocognitive impairment persist among people living with HIV (PLWH), despite being virally suppressed on antiretroviral therapy. PLWH are disproportionally impacted by physiological and psychosocial comorbidities compared to those without HIV. As adults live longer with HIV, the neurocognitive burden of physiological and psychosocial stressors can impair everyday functioning and may contribute to the development of neurodegenerative diseases such as Alzheimer's disease. This article outlines neurocognitive consequences of everyday stressors in PLWH. While some lifestyle factors can exacerbate inflammatory processes and promote negative neurocognitive health, novel interventions including the use of cannabinoids may be neuroprotective for aging PLWH who are at risk for elevated levels of inflammation from comorbidities. Studies of integrated neurocognitive rehabilitation strategies targeting lifestyle factors are promising for improving neurocognitive health, and may over time, reduce the risk of Alzheimer's disease in PLWH.

Indexed as

Alzheimer DiseaseHIV InfectionsAgingComorbidityHumansAgingAlzheimer’s diseaseHIVneurocognitive impairmentneuroinflammation

Identifiers

PMID37599532
PMCPMC12320509
OpenAlexW4385977739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.