ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023
Evaluation of Kato-Katz and multiplex quantitative polymerase chain reaction performance for clinical helminth infections in Thailand using a latent class analysis.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Molecular evidence of a high prevalence of Opisthorchis viverrini infection in an endemic community in Sakon Nakhon Province, northeastern Thailand.Tropical medicine and health · 2026Article
- Shared urinary metabolomic signatures as potential biomarkers for early intestinalCurrent research in parasitology & vector-borne diseases · 2026Article
- Mathematical modeling of control strategies for the elimination of soil-transmitted helminthiases in Thailand.PLoS neglected tropical diseases · 2025Article
- Baseline Assessment of Taeniasis and Cysticercosis Infections in a High-Priority Region forPathogens (Basel, Switzerland) · 2025Article
- Evaluation of the Allplex GI Parasite and Helminth PCR Assay in a Belgian Travel Clinic.Diagnostics (Basel, Switzerland) · 2024Article
- Identification of trans-genus biomarkers for early diagnosis of intestinal schistosomiasis and progression of gut pathology in a mouse model using metabolomics.PLoS neglected tropical diseases · 2024Article
- Evaluation of Kato-Katz and multiplex quantitative polymerase chain reaction performance for clinical helminth infections in Thailand using a latent class analysis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Introduction to the special issue: challenges and opportunities in the fight against neglected tropical diseases: a decade from the London Declaration on NTDs.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
Abstract
Using an appropriate diagnostic tool is essential to soil-transmitted helminth control and elimination efforts. Kato-Katz (KK) is the most commonly used diagnostic, but recently other tools, such as real-time quantitative polymerase chain reaction (multiplex qPCR), are starting to be employed more. Here, we evaluated the performance of these two diagnostic tools for five helminth species in Thailand. In the absence of a gold standard, diagnostic performance can be evaluated using latent class analysis. Our results suggest that in moderate to high prevalence settings above 2% multiplex qPCR could be more sensitive than KK, this was particularly apparent for
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Registered trials
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