Evidence map›Paper›PMID 37598401›Full record

Trial reportClinical autonomic research : official journal of the Clinical Autonomic Research Society2023

Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial.

Courtney M Wheatley-Guy, Meredith G Shea, Jordan K Parks, Robert Scales, Brent P Goodman, Richard J Butterfield, Bruce D Johnson

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS).Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Pooled it
  2. Trial
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  4. Patient perspectives on exercise among adults with postural orthostatic tachycardia syndrome: a mixed methods study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Courtney M Wheatley-GuyDivision of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ, 85259, USA. wheatley.courtney@mayo.edu.ORCID 0000-0002-2854-462X
Meredith G SheaDivision of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ, 85259, USA.
Jordan K ParksDivision of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ, 85259, USA.
Robert ScalesDivision of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ, 85259, USA.
Brent P GoodmanDepartment of Neurology, Mayo Clinic, Scottsdale, AZ, USA.
Richard J ButterfieldDepartment of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ, USA.
Bruce D JohnsonDivision of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ, 85259, USA.
Mayo Clinic in Arizona · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

purposeExercise like any medication requires the correct dose; to be effective the appropriate frequency, duration, and intensity are necessary. This study aimed to assess if a semi-supervised exercise training (ET) program would be more effective at improving aerobic fitness (VO

methodsSubjects were randomized to either the ET or SOC groups (n 26 vs. 23; age 33 ± 11 vs. 37 ± 10 years; VO

resultsThe ET group demonstrated a greater improvement in VO

conclusionExercise training was more effective with greater improvements in aerobic fitness, orthostatic symptoms, and exercise tolerance for individuals with POTS when intensity and progression were personalized and delivered with minimal supervision compared to the SOC.

Indexed as

Orthostatic IntolerancePostural Orthostatic Tachycardia SyndromeAdultAutonomic Nervous SystemExerciseExercise TestHumansYoung AdultCardiopulmonary exercise testing (VO2)COMPASS 31Exercise tolerancePersonalized exercise program

Identifiers

PMID37598401
PMCPMC10751269
OpenAlexW4386011454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.