Evidence map›Paper›PMID 37598398›Full record

ArticleMagnetic resonance in medicine2024

Learning ADC maps from accelerated radial k-space diffusion-weighted MRI in mice using a deep CNN-transformer model.

Yuemeng Li, Miguel Romanello Joaquim, Stephen Pickup, Hee Kwon Song, Rong Zhou, Yong Fan

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuemeng LiCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-8796-1503
Miguel Romanello JoaquimDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4219-1880
Stephen PickupDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hee Kwon SongDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rong ZhouDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yong FanCenter for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · US

Funding

Personalized Functional Network Modeling to Characterize and Predict Psychopathology in YouthR01EB022573 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Yong Fan, Theodore Satterthwaite · 2016 to 2026
$6.0M
Individualized Closed Loop TMS for Working Memory EnhancementR01MH120811 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI FAN, YONG, OATHES, DESMOND · 2019 to 2023
$3.5M
Fast and robust deep learning tools for analysis of neuroimaging data of Alzheimer's diseaseR01AG066650 · NIA · UNIVERSITY OF PENNSYLVANIA · PI FAN, YONG · 2021 to 2025
$3.4M
Penn Quantitative MRI Resource for Pancreatic CancerU24CA231858 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ODWYER, PETER J, ROSEN, MARK ALAN · 2018 to 2022
$3.0M
NCI NIH HHS U24 CA231858NIA NIH HHS R01 AG066650NIBIB NIH HHS R01 EB022573NIMH NIH HHS R01 MH120811
6 · The paper itself

Abstract

purposeTo accelerate radially sampled diffusion weighted spin-echo (Rad-DW-SE) acquisition method for generating high quality ADC maps.

methodsA deep learning method was developed to generate accurate ADC maps from accelerated DWI data acquired with the Rad-DW-SE method. The deep learning method integrates convolutional neural networks (CNNs) with vision transformers to generate high quality ADC maps from accelerated DWI data, regularized by a monoexponential ADC model fitting term. A model was trained on DWI data of 147 mice and evaluated on DWI data of 36 mice, with acceleration factors of 4× and 8× compared to the original acquisition parameters.

resultsAblation studies and experimental results have demonstrated that the proposed deep learning model generates higher quality ADC maps from accelerated DWI data than alternative deep learning methods under comparison when their performance is quantified in whole images as well as in regions of interest, including tumors, kidneys, and muscles.

conclusionsThe deep learning method with integrated CNNs and transformers provides an effective means to accurately compute ADC maps from accelerated DWI data acquired with the Rad-DW-SE method.

Indexed as

Diffusion Magnetic Resonance ImagingNeural Networks, ComputerAnimalsMiceapparent diffusion coefficientconvolutional neural networkdiffusion weighted MRImonoexponential modelparametric estimationself-attention

Identifiers

PMID37598398
PMCPMC10691280
OpenAlexW4385965171

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.