ArticleCytotherapy2023
Comparison of Haemonetics Cell Saver 5+ and manual density separation for optimum depletion of red blood cells and preservation of CD34
Article in Cytotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND
aimsThe current approach for preventing hemolysis of red blood cells (RBCs) in major ABO-incompatible bone marrow (BM) grafts after infusion is to deplete RBCs from BM products before transplantation. Traditionally, manual density separation (MDS) using Ficoll-Hypaque (Cytiva Sweden AB, Uppsala, Sweden has been used to accomplish RBC depletion. This process yields good CD34
methodsThis retrospective analysis comprised data from 58 allogeneic BM grafts. RBC depletion and CD34
resultsLinear regression analysis of log transformation of CD34
conclusionsWe provide evidence that an automated method using Haemonetics Cell Saver 5+ achieves RBC depletion and CD34
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