ArticleBMC oral health2023
The effect of nanobased irrigants on the root canal dentin microhardness: an ex-vivo study.
Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Assessment of the dentine microhardness following the application of different intracanal medicaments. An in-vitro study.BDJ open · 2026Article
- Dentin microhardness changes and smears layer removal following conventional versus alternative irrigation regimens in root canals.Bioinformation · 2026Article
- Evaluation of EDTA and silver nanoparticle based root canal irrigants on smear layer elimination and dentine surface roughness.Bioinformation · 2026Article
- In vitro evaluation of dye penetration and dentin microhardness after laser irradiation using photon-induced photoacoustic streaming and shock wave enhanced emission photoacoustic streaming tips compared to ultrasonic activation.Lasers in medical science · 2025Article
- Nanoarchitectonics-Based Materials as a Promising Strategy in the Treatment of Endodontic Infections.Pharmaceutics · 2024Review
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Authors and funding
5 authors.
Funding
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Abstract
backgroundGiven the favorable antimicrobial properties of zinc oxide (ZnONPs), standard silver (AgNPs), and imidazolium-based silver (Im-AgNPs) nanoparticles, this study aimed to evaluate their influence on the microhardness of root canal dentin.
methodsIn this experimental study, 40 mandibular premolars were decoronated at the cementoenamel junction and longitudinally sectioned into halves to create 80 specimens. They were randomly allocated to 5 groups (n = 16) and irrigated with ZnONPs, AgNPs, Im-AgNPs, NaOCl, or normal saline (as the negative control) for 15 min. The Vickers Hardness Number (VHN) was measured on each root canal third before and after being soaked in irrigants. Statistical analysis was performed using paired t-test, one-way ANOVA, and post hoc Tukey's test (α = 0.05).
resultsIm-AgNPs and ZnONPs irrigants improved the microhardness of root dentin, whereas, AgNPs and NaOCl decreased it. ZnONPs yielded the highest VHN at the coronal third (P˂0.001), while the Im-AgNPs provided the highest VHN at the middle and apical thirds (P˂0.001). The AgNPs group showed the lowest VHN at the apical third.
conclusionsThe irrigants containing Im-AgNPs and ZnONPs significantly enhanced the root dentin microhardness. However, the use of AgNPs resulted in decreased microhardness.
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