Evidence map›Paper›PMID 37598149›Full record

ArticleDiagnostic pathology2023

The value of deep neural networks in the pathological classification of thyroid tumors.

Chengwen Deng, Dan Li, Ming Feng, Dongyan Han, Qingqing Huang

Open access · goldAbstract read
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Article in Diagnostic pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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  8. Trends in AI-powered Classification of Thyroid Neoplasms Based on Histopathology Images - a Systematic Review.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Chengwen Deng *Department of Nuclear Medicine, Chaohu Hospital of Anhui Medical University, Heifei, 238000, China.
Dan Li *Department of Nuclear Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510289, China.
Ming Feng *Tongji University, Shanghai, 200082, China.
Dongyan HanShanghai Tenth People's Hospital Tongji University, Shanghai, 200072, China.
Qingqing HuangShanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China. qingqinghuang80@163.com.
Chaohu Hospital of Anhui Medical University · CNShanghai Tenth People's Hospital · CNShanghai University of Medicine and Health Sciences · CNSun Yat-sen University · CNTongji University · CN

Funding

Construction project of Shanghai Key Laboratory of Molecular Imaging 18DZ2260400
6 · The paper itself

Abstract

backgroundTo explore the distinguishing diagnostic value and clinical application potential of deep neural networks (DNN) for pathological images of thyroid tumors.

methodsA total of 799 pathological thyroid images of 559 patients with thyroid tumors were retrospectively analyzed. The pathological types included papillary thyroid carcinoma (PTC), medullary thyroid carcinoma (MTC), follicular thyroid carcinoma (FTC), adenomatous goiter, adenoma, and normal thyroid gland. The dataset was divided into a training set and a test set. Resnet50, Resnext50, EfficientNet, and Densenet121 were trained using the training set data and tested with the test set data to determine the diagnostic efficiency of different pathology types and to further analyze the causes of misdiagnosis.

resultsThe recall, precision, negative predictive value (NPV), accuracy, specificity, and F1 scores of the four models ranged from 33.33% to 100.00%. The area under curve (AUC) ranged from 0.822 to 0.994, and the Kappa coefficient ranged from 0.7508 to 0.7713. However, the performance of diagnosing FTC, adenoma, and adenomatous goiter was slightly inferior to other types of pathological tissues.

conclusionThe DNN model achieved satisfactory results in the task of classifying thyroid tumors by learning thyroid pathology images. These results indicate the potential of the DNN model for the efficient diagnosis of thyroid tumor histopathology.

Indexed as

Adenocarcinoma, FollicularThyroid NeoplasmsHumansNeural Networks, ComputerRetrospective StudiesArtificial intelligenceDeep neural networkDiagnosticsPathologyThyroid tumor

Identifiers

PMID37598149
PMCPMC10439627
OpenAlexW4386001070

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.