ArticleBehavior therapy2023
Unified Protocol vs Trauma-Focused Cognitive Behavioral Therapy Among Adolescents With PTSD.
Article in Behavior therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Youth Anxiety Measure for DSM-5 (YAM-5): An Updated Systematic Review of its Psychometric Properties.Child psychiatry and human development · 2026Pooled it
- A randomized controlled effectiveness trial of transdiagnostic treatment and measurement-based care for adolescents with emotional disorders in community clinics.Journal of consulting and clinical psychology · 2025Trial
- Article
- Efficacy of an internet-based version of the unified protocol for transdiagnostic treatment of emotional disorders in adolescents (iUP-A): A randomized active-controlled trial.Internet interventions · 2026Article
- An Iteratively Adapted Transdiagnostic Prevention Program for Diverse High School Settings (U-PEACE): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Article
- Understanding Selective Mutism in Very Young Children.Behavioral sciences (Basel, Switzerland) · 2025Review
- Are the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents as Effective for OCD as for Anxiety and Depression?Children (Basel, Switzerland) · 2025Article
- Network Structure of Transdiagnostic Dimensions of Emotional Disorders in Adolescents With Subthreshold Anxiety and Depression: Links With Psychopathology and Socio-Emotional Adjustment.Early intervention in psychiatry · 2025Article
- Comprehensive evaluation of the efficacy and patient acceptance of combined antidepressant and cognitive behavioral therapy in the treatment of post-traumatic stress disorder.Frontiers in psychiatry · 2025Article
- Reply to Wei and Li: Commentary on Expanding Perspectives on Treatment Outcomes in Clinical High-Risk for Psychosis.Early intervention in psychiatry · 2024Article
- Impact of trauma exposure and depression comorbidity on response to transdiagnostic behavioral therapy for pediatric anxiety and depression.Npj mental health research · 2024Article
- An emotion regulation skills training for adolescents and parents: perceptions and acceptability of methodological aspects.Frontiers in psychiatry · 2024Article
- Review
- Resilience, Coping, and the Covid-19 Pandemic Across the Globe - an Update: What Have we Learned?Clinical neuropsychiatry · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Harmful consequences of COVID-19, such as prolonged quarantine, lack of social contact, and especially loss of parents or friends, can negatively impact children and adolescents' mental health in diverse ways, including engendering posttraumatic stress symptoms. Our study is the first to compare the transdiagnostic Unified Protocol for the Treatment of Emotional Disorders in Adolescents (UP-A; Ehrenreich et al., 2009; Ehrenreich-May et al., 2017) with Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) in terms of outcomes related to PTSD symptoms (COVID-19-related vs. COVID-19 unrelated PTSD) and comorbid symptoms (i.e., anxiety, depression) and other measures (i.e., emotion regulation, self-injury, anger). Individuals diagnosed with PTSD were randomly assigned to the UP-A (n = 46) or TF-CBT group (n = 47), administered the SCID-5 and a battery of measures and followed up posttreatment and then after 3, 6, and 9 months. Ninety-three adolescents with PTSD were enrolled, 45% boys and 61% COVID-19-related PTSD. We adopted an intention-to-treat approach. At the initial post-intervention assessment, except for emotion regulation and unexpressed angry feelings, in which UP-A participants reported greater reductions, no significant differences in other variables were secured between the UP-A and TF-CBT. However, at follow-up assessments, the UP-A evidenced significantly better outcomes than TF-CBT. We found support for the UP-A compared with TF-CBT in treating adolescents with PTSD, regardless of COVID-19-related PTSD status, in maintaining treatment effectiveness over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.