Evidence map›Paper›PMID 37597692›Full record

ReviewAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2023

Emerging concepts in neuropathic and neurogenic itch.

Kelsey L Auyeung, Brian S Kim

Abstract readReview
In one paragraph

Review in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Maladaptive immunity to the microbiota promotes neuronal hyperinnervation and itch via IL-17A.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Beyond the classic players: Mas-related G protein-coupled receptor member X2 role in pruritus and skin diseases.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Acta dermato-venereologica · 2024
    Article
  18. Article
  19. Chronic pruritus: a narrative review.Anais brasileiros de dermatologia
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kelsey L AuyeungKimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.
Brian S KimKimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York; Mark Lebwohl Center for Neuroinflammation & Sensation, Icahn School of Medicine at Mount Sinai, New York, New York; Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: brian.kim3@mountsinai.org.

Funding

Neuroimmune Regulation of Atopic DermatitisR01AR070116 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2016 to 2021
$3.8M
Defining the role of IL-18 in atopic dermatitisR01AI176660 · NIAID · WASHINGTON UNIVERSITY · PI Brian Kim, Steven Van Dyken · 2023 to 2026
$3.3M
Regulation of IgE and Atopic ItchR01AI167933 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CONROY, MICHELLE E, KIM, BRIAN · 2022 to 2025
$3.2M
Natural Killer Cell Regulation of Skin InflammationR01AR077007 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2021 to 2025
$2.5M
The Role of IL-33 in Chronic ItchR21AI167047 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KIM, BRIAN · 2021 to 2022
$460k
NIAID NIH HHS R01 AI167933NIAID NIH HHS R01 AI176660NIAID NIH HHS R21 AI167047NIAMS NIH HHS R01 AR070116NIAMS NIH HHS R01 AR077007
6 · The paper itself

Abstract

Chronic pruritus has multiple etiologies, ranging from inflammatory to metabolic and neuropathic processes. However, recent advances in itch biology have shed light on potential mechanisms that explain the molecular and cellular basis of these pathologies. Furthermore, new understanding of neuroimmune itch circuits necessitates clarification of terminologies such as "neuropathic" and "neurogenic." This review provides an overview of ways new concepts may better explain the pathophysiology of a variety of chronic pruritic disorders and the rationale for directing emerging novel therapeutic strategies toward them.

Indexed as

PruritusChronic DiseaseHumans

Identifiers

PMID37597692
PMCPMC10840634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.