Evidence map›Paper›PMID 37596922›Full record

SynthesisAge and ageing2023

Perioperative interventions to improve early mobilisation and physical function after hip fracture: a systematic review and meta-analysis.

Mitchell N Sarkies, Luke Testa, Ann Carrigan, Natalie Roberts, Rene Gray, Catherine Sherrington, Rebecca Mitchell, Jacqueline C T Close, Catherine McDougall, Katie Sheehan

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 5 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Mitchell N SarkiesSchool of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney NSW 2006, Australia.ORCID 0000-0001-7318-3598
Luke TestaAustralian Institute of Health Innovation, Faculty of Medicine, Health and Human Sciences, Macquarie University, Macquarie Park NSW 2113, Australia.ORCID 0000-0003-4447-6628
Ann CarriganAustralian Institute of Health Innovation, Faculty of Medicine, Health and Human Sciences, Macquarie University, Macquarie Park NSW 2113, Australia.
Natalie RobertsAustralian Institute of Health Innovation, Faculty of Medicine, Health and Human Sciences, Macquarie University, Macquarie Park NSW 2113, Australia.
Rene GrayJames Paget University Hospital Foundation Trust, Norfolk NR31, UK.
Catherine SherringtonInstitute for Musculoskeletal Health, The University of Sydney and Sydney Local Health District, Sydney NSW 2006, Australia.
Rebecca MitchellAustralian Institute of Health Innovation, Faculty of Medicine, Health and Human Sciences, Macquarie University, Macquarie Park NSW 2113, Australia.
Jacqueline C T CloseFalls, Balance and Injury Research Centre, Neuroscience Research Australia, Sydney NSW 2031, Australia.
Catherine McDougallThe University of Queensland, Brisbane 4072, Australia.
Katie SheehanDepartment of Population Health Sciences, School of Life Course and Population Sciences, King's College London, London WC2R, UK.ORCID 0000-0002-5325-7454
Australian Hearing · AUThe University of Sydney · AUJames Paget University Hospital · GBKing's College London · GBThe University of Queensland · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative interventions could enhance early mobilisation and physical function after hip fracture surgery.

objectiveDetermine the effectiveness of perioperative interventions on early mobilisation and physical function after hip fracture.

methodsOvid MEDLINE, CINAHL, Embase, Scopus and Web of Science were searched from January 2000 to March 2022. English language experimental and quasi-experimental studies were included if patients were hospitalised for a fractured proximal femur with a mean age 65 years or older and reported measures of early mobilisation and physical function during the acute hospital admission. Data were pooled using a random effect meta-analysis.

resultsTwenty-eight studies were included from 1,327 citations. Studies were conducted in 26 countries on 8,192 participants with a mean age of 80 years. Pathways and models of care may provide a small increase in early mobilisation (standardised mean difference [SMD]: 0.20, 95% confidence interval [CI]: 0.01-0.39, I2 = 73%) and physical function (SMD: 0.07, 95% CI 0.00 to 0.15, I2 = 0%) and transcutaneous electrical nerve stimulation analgesia may provide a moderate improvement in function (SMD: 0.65, 95% CI: 0.24-1.05, I2 = 96%). The benefit of pre-operative mobilisation, multidisciplinary rehabilitation, recumbent cycling and clinical supervision on mobilisation and function remains uncertain. Evidence of no effect on mobilisation or function was identified for pre-emptive analgesia, intraoperative periarticular injections, continuous postoperative epidural infusion analgesia, occupational therapy training or nutritional supplements.

conclusionsPerioperative interventions may improve early mobilisation and physical function after hip fracture surgery. Future studies are needed to model the causal mechanisms of perioperative interventions on mobilisation and function after hip fracture.

Indexed as

Early AmbulationHip FracturesPerioperative CareAgedAged, 80 and overBicyclingDietary SupplementsHumansPain Managementanalgesiamodel of careolder peoplepost-operativepre-operativesurgerysystematic review

Identifiers

PMID37596922
PMCPMC10439513
OpenAlexW4385998268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.