Evidence map›Paper›PMID 37596613›Full record

ArticleTrials2023

Clinical trial protocol for P-NeLoP: a randomized controlled trial comparing the feasibility and outcomes of robot-assisted partial nephrectomy with low insufflation pressure using AirSeal versus standard insufflation pressure (UroCCR no. 85 study).

Gaelle Margue, Pierre Bigot, Alexandre Ingels, Morgan Roupret, Thibaut Waeckel, Jean-Alexandre Long, Géraldine Pignot, Karim Bensalah, Hervé Lang, Jonathan Olivier and 7 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05404685 (Randomised Study to Assess the Feasibility and Outcomes of Robotic Assisted Partial Nephrectomy in Low Pressure With AirSeal), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05404685 nacompletednot on this map

Randomised Study to Assess the Feasibility and Outcomes of Robotic Assisted Partial Nephrectomy in Low Pressure With AirSeal

TypeinterventionalSponsorUniversity Hospital, BordeauxRan2022 to 2024Enrolled280ConditionsKidney Tumors Treated With Minimally Invasive SurgeryArmsLow insufflation pressure (7mm Hg) for Robotic Assisted Partial Nephrectomy, Standard insufflation pressure (12mm Hg) for Robotic Assisted Partial Nephrectomy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A comparison of COJournal of robotic surgery · 2025
    Pooled it
  2. Impact of the AirSealJournal of robotic surgery · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Gaelle MargueUrology Department, Bordeaux University Hospital, Bordeaux, France. gaelle.margue@chu-bordeaux.Fr.ORCID http://orcid.org/0000-0001-5311-1597
Pierre BigotUrology Department, Angers University Hospital, Angers, France.
Alexandre IngelsUrology Department, Henri Mondor University Hospital, APHP, Paris, France.
Morgan RoupretUrology Department, Pitié-Saplétrière Hospital, APHP, Paris, France.
Thibaut WaeckelUrology Department, Caen University Hospital, Caen, France.
Jean-Alexandre LongUrology Department, Grenoble Alpes University Hospital, Grenoble, France.
Géraldine PignotUrology Department, Paoli-Calmettes Institut, Marseille, France.
Karim BensalahUrology Department, Rennes University Hospital, Rennes, France.
Hervé LangUrology Department, Strasbourg University Hospital, Strasbourg, France.
Jonathan OlivierUrology Department, Lille University Hospital, Lille, France.
Franck BruyereUrology Department, Tours University Hospital, Tours, France.
Matthieu DurandUrology Department, Nice University Hospital, Nice, France.
Jean-Baptiste BeauvalUrology Department, La Croix du Sud Hospital, Quint-Fonsegrives, France.
Richard MalletUrology Department, Polyclinique Francheville, Perigueux, France.
Bastien ParierUrology Department, Kremlin Bicetre, APHP, Paris, France.
Alexandre De La TailleUrology Department, Henri Mondor University Hospital, APHP, Paris, France.
Jean-Christophe BernhardUrology Department, Bordeaux University Hospital, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robot-assisted partial nephrectomy (RAPN) is the standard of care for small, localized kidney tumors. This surgery is conducted within a short hospital stay and can even be performed as outpatient surgery in selected patients. In order to allow early rehabilitation of patients, an optimal control of postoperative pain is necessary. High-pressure pneumoperitoneum during surgery seems to be the source of significant pain during the first hours postoperatively. Our study is a prospective, randomized, multicenter, controlled study which aims to compare post-operative pain at 24 h between patients undergoing RAPN at low insufflation pressure (7 mmHg) and those operated on at standard pressure (12 mmHg) using the AirSeal system.This trial is registered in the US National Library of Medicine Trial Registry (NCT number: NCT05404685).

Indexed as

InsufflationRoboticsFeasibility StudiesHumansMulticenter Studies as TopicNephrectomyPostoperative PainProspective StudiesRandomized Controlled Trials as TopicInsufflation pressureKidney cancerPost-operative painRobot-assisted partial nephrectomy

Identifiers

PMID37596613
PMCPMC10439590

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.