Evidence map›Paper›PMID 37596558›Full record

ArticleBMC biotechnology2023

Determination of serum CA724 levels using fluorescence immunochromatography.

Chang Liu, Cuicui Chen, Fenglan Peng, Huankun Liang, Shuhai Zhong, Tiancai Liu, Laiqing Li, Alexander Boronin, Wenqi Dong

Open access · goldAbstract read
In one paragraph

Article in BMC biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Chang Liu *Heilongjiang Academy of Chinese Medicine Sciences, Harbin, 150036, China.
Cuicui Chen *Guangzhou Youdi Bio-technology Co., Ltd, Guangzhou, 510663, China.
Fenglan PengTaian Disabled Soldiers' Hospital of Shandong Province, Taian, 271000, China.
Huankun LiangGuangzhou Youdi Bio-technology Co., Ltd, Guangzhou, 510663, China.
Shuhai ZhongGuangzhou Youdi Bio-technology Co., Ltd, Guangzhou, 510663, China.
Tiancai LiuSchool of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, 510515, China.
Laiqing LiGuangzhou Youdi Bio-technology Co., Ltd, Guangzhou, 510663, China.
Alexander BoroninLaboratory of Plasmid Biology, G.K. Skryabin Institute Of Biochemistry and Physiology of Microorganisms Russian Academy of Sciences, Pushchino, 142290, Russia.
Wenqi DongGuangzhou Zhenda Biopharmaceutical Technology Co., Ltd, No. 3 Juquan Road, Huangpu District, Guangzhou, 510663, China. dongwenqi63@163.com.
Coal Industry Jinan Design & Research Institute (China) · CNG. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms · RUSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarbohydrate antigen 724 (CA724) is a sensitive and specific indicator for multiple malignant tumors. The aim of this study was to establish a Eu-time resolved fluorescence immunochromatography (Eu-TRFICO) method for quantitative detection of CA724 in serum.

methodsEu-TRFICO strips were optimized and assembled. The sensitivity, specificity and precision were evaluated using CA724 standard dilutions and matrix serum. Meanwhile, the reference interval, comparison, and sensitivity/specificity were performed using clinical negative/positive gastric cancer serum samples.

resultsThe standard curve equation was y = 9.869 x - 154.12 (R

conclusionThis study prepared Eu-TRFICO strips with high sensitivity, specificity, precision and satisfactory clinical testing performance, which provides more options for clinical quantitative and convenient testing of CA724.

Indexed as

Stomach NeoplasmsChromatography, AffinityHumansImmunologic TestsBiomarkerCA724EuGastric cancerTime-resolved fluorescence immunochromatography

Identifiers

PMID37596558
PMCPMC10436430
OpenAlexW4385985070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.