Evidence map›Paper›PMID 37596361›Full record

ArticleScientific reports2023

Inhibitory effects of Schisandrin C on collagen behavior in pulmonary fibrosis.

Mingchen Xu, Chenghe Zhao, Haiming Song, Chunmei Wang, He Li, Xudong Qiu, He Jing, Wenyue Zhuang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mingchen Xu *Department of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China.
Chenghe Zhao *Department of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China.
Haiming SongDepartment of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China.
Chunmei WangDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, China.
He LiDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, China.
Xudong QiuDepartment of Hand Surgery, Affiliated Hospital, Beihua University, Jilin, China.
He JingDepartment of Hand Surgery, Affiliated Hospital, Beihua University, Jilin, China.
Wenyue ZhuangDepartment of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China. wenyuezhuang@163.com.
Beihua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary fibrosis (PF) is a serious progressive fibrotic disease that is characterized by excessive accumulation of extracellular matrix (ECM), thus resulting in stiff lung tissues. Lysyl oxidase (LOX) is an enzyme involved in fibrosis by catalyzing collagen cross-linking. Studies found that the ingredients in schisandra ameliorated bleomycin (BLM)-induced PF, but it is unknown whether the anti-PF of schisandra is related to LOX. In this study, we established models of PF including a mouse model stimulated by BLM and a HFL1 cell model induced by transforming growth factor (TGF)-β

Indexed as

LignansPolycyclic CompoundsPulmonary FibrosisAnimalsCollagenCyclooctanesMiceCollagenCyclooctanesLignansPolycyclic Compoundsschizandrinschizandrin C

Identifiers

PMID37596361
PMCPMC10439186
OpenAlexW4385978333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.