Evidence map›Paper›PMID 37596343›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Multi-task deep learning-based radiomic nomogram for prognostic prediction in locoregionally advanced nasopharyngeal carcinoma.

Bingxin Gu, Mingyuan Meng, Mingzhen Xu, David Dagan Feng, Lei Bi, Jinman Kim, Shaoli Song

Abstract readComment
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Should end-to-end deep learning replace handcrafted radiomics?European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. IntegratingBMC cancer · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Bingxin Gu *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Mingyuan Meng *School of Computer Science, the University of Sydney, Sydney, Australia.
Mingzhen Xu *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
David Dagan FengSchool of Computer Science, the University of Sydney, Sydney, Australia.
Lei BiInstitute of Translational Medicine, National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jinman KimSchool of Computer Science, the University of Sydney, Sydney, Australia.
Shaoli SongDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China. shaoli-song@163.com.ORCID 0000-0003-2544-7522

Funding

Australian Research Council DP200103748National Natural Science Foundation of China 82272035Special Clinical Research Project of Health Industry of Shanghai Municipal Health Commission 20224Y0238
6 · The paper itself

Abstract

purposePrognostic prediction is crucial to guide individual treatment for locoregionally advanced nasopharyngeal carcinoma (LA-NPC) patients. Recently, multi-task deep learning was explored for joint prognostic prediction and tumor segmentation in various cancers, resulting in promising performance. This study aims to evaluate the clinical value of multi-task deep learning for prognostic prediction in LA-NPC patients.

methodsA total of 886 LA-NPC patients acquired from two medical centers were enrolled including clinical data, [

resultsOur MTDLR nomogram achieved C-index of 0.818 (95% confidence interval (CI): 0.785-0.851), 0.752 (95% CI: 0.638-0.865), and 0.717 (95% CI: 0.641-0.793) and area under curve (AUC) of 0.859 (95% CI: 0.822-0.895), 0.769 (95% CI: 0.642-0.896), and 0.730 (95% CI: 0.634-0.826) in the training, internal validation, and external validation cohorts, which showed a statistically significant improvement over conventional radiomic nomograms. Our nomogram also divided patients into significantly different high- and low-risk groups.

conclusionOur study demonstrated that MTDLR nomogram can perform reliable and accurate prognostic prediction in LA-NPC patients, and also enabled better patient stratification, which could facilitate personalized treatment planning.

Indexed as

Deep LearningNasopharyngeal NeoplasmsFluorodeoxyglucose F18HumansNasopharyngeal CarcinomaNomogramsPositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesFluorodeoxyglucose F18Deep learningNasopharyngeal carcinomaPET/CTRadiomicsSurvival prediction

Identifiers

PMID37596343
PMCPMC10611876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.