ArticleScientific reports2023
Antimicrobial and mechanical assessment of cellulose-based thermoformable material for invisible dental braces with natural essential oils protecting from biofilm formation.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Antibiofilm Activity of a Thermoformable Material Loaded With Essential Oil Solution.Clinical and experimental dental research · 2026Article
- Antimicrobial effect of treating thermoformable cellulose-based materials with essential oils.Clinical oral investigations · 2026Article
- Evaluation of Antibacterial Effect and Mechanical Properties of Thermoformed Clear Aligners Coated with Chitosan and Cellulose Nanocrystals.Journal of dentistry (Shiraz, Iran) · 2026Article
- Femtosecond laser-induced micro/nanostructures loaded with silver nanoparticles on clear aligners prevent bacterial infection.BMC oral health · 2026Article
- Next-Generation Orthodontics: Functional Resins, Biomechanics, Biocompatibility, and Current Clinical Reality of Direct 3D-Printed Aligners.Journal of functional biomaterials · 2026Review
- An overview of types of antibacterial coatings and methods for creating them on orthodontic wires.Journal of materials science. Materials in medicine · 2025Review
- In Vitro Evaluation of Biofilm Formation by Oral Microorganisms on Clear Aligner Materials: Influence of Mouthwash Exposure.Journal of functional biomaterials · 2025Article
- Cytotoxicity and Endocrine Disruption in Materials Used for Removable Orthodontic Retainers: A Comprehensive Review.Dentistry journal · 2025Review
- Essential Oils for Biofilm Control: Mechanisms, Synergies, and Translational Challenges in the Era of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances.iScience · 2024Review
- Changes in the Oral Microbiota with the Use of Aligners vs. Braces: A Systematic Review.Journal of clinical medicine · 2024Review
- Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle.Nature communications · 2024Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Controlling biofilm formation in the oral cavity during orthodontic treatments is crucial. Therefore, antimicrobial surfaces for invisible dental appliances are of interest to both therapists and patients. Here we present a cellulose-based thermoformable material used for invisible braces that can be loaded with essential oils (EOs) having antibacterial and antifungal properties. We hypothesize that this material can absorb and release EOs, thus providing an antimicrobial effect without compromising the safety and mechanical properties necessary for dental invisible braces. Conventional microbiology and isothermal microcalorimetry analyses revealed that the thermoformable material loaded with essential oils significantly delayed the biofilm formation of oral streptococci (S. mutans and S. mitis) under static conditions (p < 0.05) and while simulating saliva flow (p < 0.05). In addition, cytotoxicity tests (ISO 10993-5), revealed that the loaded material is well tolerated by human gingival fibroblasts. Finally, the loading with antibacterial agents did not significantly alter the mechanical properties and stability of the material (initial force (p = 0.916); initial stress (p = 0.465)). Compared to gold-standard clear aligner materials, this material offers a reliable transmission of forces for orthodontic treatments. Moreover, this approach exhibits the potential for acting as an oral drug delivery platform for multiple compounds.
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Registered trials
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