Evidence map›Paper›PMID 37596047›Full record

ArticleeNeuro2023

The Novel Somatosensory Nose-Poke Adapted Paradigm (SNAP) Is an Effective Tool to Assess Differences in Tactile Sensory Preferences in Autistic-Like Mice.

Matthew S Binder, Angelique Bordey

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew S BinderDepartments of Neurosurgery and Cellular and Molecular Physiology, Wu Tsai Institute, Yale School of Medicine, New Haven, CT 06520-8082.
Angelique BordeyDepartments of Neurosurgery and Cellular and Molecular Physiology, Wu Tsai Institute, Yale School of Medicine, New Haven, CT 06520-8082 angelique.bordey@yale.edu.ORCID 0000-0003-3496-3385
Yale University · US

Funding

Role of mTORC1 dependent translation in neurological deficits of TSCF32NS123002 · NINDS · YALE UNIVERSITY · PI BINDER, MATTHEW · 2022 to 2023
$83k
NINDS NIH HHS F32 NS123002
6 · The paper itself

Abstract

One of the most prevalent deficits in autism spectrum disorder (ASD) are sensitivities to sensory stimuli. Despite the prevalence of sensory deficits in autism, there are few paradigms capable of easily assessing sensory behaviors in ASD-like mouse models. We addressed this need by creating the Somatosensory Nose-poke Adapted Paradigm (SNAP), which consists of an elevated platform with 6 holes in the center, half of which are lined with sandpaper and half are smooth, requiring mice to use their whiskers to sense the texture. The SNAP paradigm assesses tactile sensory preferences as well as stereotypy, anxiety, and locomotion. We used two wild-type (neurotypical) mouse strains, C57BL/6J (C57) inbred and CD-1 outbred mice, and two ASD mouse models, BTBR (a model of idiopathic ASD) and

Indexed as

Autism Spectrum DisorderAutistic DisorderAnimalsAnxietyDisease Models, AnimalMiceMice, Inbred C57BLStereotyped Behaviorautismbehaviorlocomotionnovel methodologysomatosensory deficitstereotypy

Identifiers

PMID37596047
PMCPMC10470849
OpenAlexW4385971458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.