Evidence map›Paper›PMID 37595584›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2023

Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences.

Kenneth Cornetta, Samantha Kay, Florence Urio, Irene Kida Minja, Erasto Mbugi, Josephine Mgaya, Teddy Mselle, Siana Nkya, Mohamed Zahir Alimohamed, Kinuma Ndaki and 7 more

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Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kenneth CornettaDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address: kcornett@iu.edu.
Samantha KayAmerican Society of Gene and Cell Therapy, Milwaukee, WI, USA.
Florence UrioDepartment of Biochemistry and Molecular Biology, School of Biomedical Sciences, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Irene Kida MinjaSPARCo-Clinical Coordinating Center - Haematology and Blood Transfusion Department, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Erasto MbugiDepartment of Biochemistry and Molecular Biology, School of Biomedical Sciences, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Josephine MgayaSPARCo-Clinical Coordinating Center - Haematology and Blood Transfusion Department, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Teddy MselleDepartment of Biochemistry and Molecular Biology, School of Biomedical Sciences, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Siana NkyaDepartment of Biochemistry and Molecular Biology, School of Biomedical Sciences, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Mohamed Zahir AlimohamedDepartment of Biochemistry and Molecular Biology, School of Biomedical Sciences, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Kinuma NdakiDepartment of Biochemistry and Molecular Biology, School of Biomedical Sciences, The Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (MUHAS).
Martín BonaminoCell and Gene Therapy Program, Research Coordination, National Cancer Institute (INCA), Rio de Janeiro, Brazil; Vice-Presidency of Research and Biological Collections (VPPCB), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Richard C KoyaDepartment of Gynecology and Obstetrics, University of Chicago Comprehensive Cancer Center, Chicago, IL, USA.
Lesha D ShahNew York University Grossman School of Medicine, New York, NY, USA.
Johnny MahlanguDepartment of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Daniela DragoSchools of Medicine and Pharmacy, University of California, San Francisco, San Francisco, CA, USA.
Savita RangarajanFaculty of Medicine, University of Southampton, Southampton, Hampshire, UK; KJ Somaiya Super Speciality Hospital and Research Centre, Mumbai, India.
Giridhara Rao JayandharanDepartment of Biological Sciences and Bioengineering, and Gangwal School of Medical Sciences and Technology and Mehta Family Center for Engineering in Medicine, Indian Institute of Technology Kanpur, Kanpur, UP, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been rapid growth in gene therapy development with an expanding list of approved clinical products. Several therapies are particularly relevant to patients in low- and middle-income countries. Moreover, investing in research and manufacturing presents an opportunity for economic development. To increase awareness of gene therapy, the American Society of Gene and Cell Therapy partnered with the Muhimbili University of Health and Allied Sciences, Tanzania, to create a certificate-bearing course. The goal was to provide faculty teaching in graduate and medical schools with the tools needed to add gene therapy to the university curriculum. The first virtual course was held in October of 2022, and 45 individuals from 9 countries in Africa completed the training. The content was new to approximately two-thirds of participants, with the remaining third indicating that the course increased their knowledge base. The program was well received and will be adapted for other under-resourced regions.

Indexed as

Cell- and Tissue-Based TherapyGenetic TherapyHumans

Identifiers

PMID37595584
PMCPMC10492022

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.