Evidence map›Paper›PMID 37595572›Full record

ArticleMolecular pharmaceutics2023

ShiZhe Shao, Michael W Stocker, Salvatore Zarrella, Timothy M Korter, Abhishek Singh, Anne Marie Healy

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

ShiZhe ShaoSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin D02 PN40, Ireland.ORCID 0000-0002-5121-8048
Michael W StockerSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin D02 PN40, Ireland.ORCID 0000-0001-7204-3892
Salvatore ZarrellaDepartment of Chemistry, Syracuse University, 1-014 Center for Science and Technology, Syracuse, New York 13244, United States.
Timothy M KorterDepartment of Chemistry, Syracuse University, 1-014 Center for Science and Technology, Syracuse, New York 13244, United States.ORCID 0000-0002-0398-5680
Abhishek SinghJanssen Pharmaceutica NV, Beerse 2340, Belgium.
Anne Marie HealySchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin D02 PN40, Ireland.ORCID 0000-0001-5093-9786
Science Foundation Ireland · IESyracuse University · USJanssen (Belgium) · BEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to investigate how different polymers affect the dissociation of cocrystals prepared by co-spray-drying active pharmaceutical ingredient (API), coformer, and polymer. Diclofenac acid-l-proline cocrystal (DPCC) was selected in this study as a model cocrystal due to its previously reported poor physical stability in a high-humidity environment. Polymers investigated include polyvinylpyrrolidone (PVP), poly(1-vinylpyrrolidone-

Indexed as

PolymersSpray DryingPhosphatesPovidoneX-Ray DiffractionPhosphatesPolymersPovidoneCocrystalCrystalline solid dispersionDissociationPolymerSpray drying

Identifiers

PMID37595572
PMCPMC10481393
OpenAlexW4385972159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.