Evidence map›Paper›PMID 37595048›Full record

ArticleScience advances2023

Imaging local diffusion in microstructures using NV-based pulsed field gradient NMR.

Fleming Bruckmaier, Robin D Allert, Nick R Neuling, Philipp Amrein, Sebastian Littin, Karl D Briegel, Philip Schätzle, Peter Knittel, Maxim Zaitsev, Dominik B Bucher

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Reconfigurable photothermal doping filament for selective spin manipulation and addressing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Optimizing ensemble NVFrontiers in quantum science and technology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fleming BruckmaierDepartment of Chemistry, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.
Robin D AllertDepartment of Chemistry, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0003-0075-2758
Nick R NeulingDepartment of Chemistry, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0003-3851-0113
Philipp AmreinDivision of Medical Physics, Department of Diagnostic and Interventional Radiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-0215-1510
Sebastian LittinDivision of Medical Physics, Department of Diagnostic and Interventional Radiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-8190-1761
Karl D BriegelDepartment of Chemistry, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0002-9745-7685
Philip SchätzleDepartment of Sustainable Systems Engineering (INATECH), University of Freiburg, Emmy-Noether-Str. 2, 79110 Freiburg, Germany.ORCID 0000-0001-7008-9299
Peter KnittelFraunhofer Institute for Applied Solid State Physics, Tullastr. 72, 79108 Freiburg, Germany.ORCID 0000-0002-2769-3615
Maxim ZaitsevDivision of Medical Physics, Department of Diagnostic and Interventional Radiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0001-7530-1228
Dominik B BucherDepartment of Chemistry, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0003-2160-0235

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding diffusion in microstructures plays a crucial role in many scientific fields, including neuroscience, medicine, or energy research. While magnetic resonance (MR) methods are the gold standard for diffusion measurements, spatial encoding in MR imaging has limitations. Here, we introduce nitrogen-vacancy (NV) center-based nuclear MR (NMR) spectroscopy as a powerful tool to probe diffusion within microscopic sample volumes. We have developed an experimental scheme that combines pulsed gradient spin echo (PGSE) with optically detected NV-NMR spectroscopy, allowing local quantification of molecular diffusion and flow. We demonstrate correlated optical imaging with spatially resolved PGSE NV-NMR experiments probing anisotropic water diffusion within an individual model microstructure. Our optically detected PGSE NV-NMR technique opens up prospects for extending the current capabilities of investigating diffusion processes with the future potential of probing single cells, tissue microstructures, or ion mobility in thin film materials for battery applications.

Identifiers

PMID37595048
PMCPMC10438442

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.