Evidence map›Paper›PMID 37595040›Full record

ArticleScience advances2023

FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer.

Yajie Liu, Kairan Yu, Xiaotian Kong, Keren Zhang, Lingyan Wang, Nana Zhang, Qiushi Chen, Mingshan Niu, Wenli Li, Xiaomin Zhong and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Yajie LiuSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0009-0006-8261-8454
Kairan YuSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0009-0005-8571-3804
Xiaotian KongFaculty of Environment and Life, Beijing University of Technology, Beijing, China.ORCID 0000-0001-7557-1674
Keren ZhangDepartment of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, China.
Lingyan WangSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0009-0000-1235-9326
Nana ZhangSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0009-0008-0487-4019
Qiushi ChenDepartment of Chemistry, The University of Hong Kong, Hong Kong, China.ORCID 0000-0001-8355-2801
Mingshan NiuBlood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China.ORCID 0000-0002-7077-6467
Wenli LiSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0000-0001-9644-1860
Xiaomin ZhongDepartment of Oncology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
Sijin WuLaboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.ORCID 0000-0003-4554-4610
Jianing ZhangSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0000-0002-4514-9197
Yubo LiuSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.ORCID 0000-0003-0645-0822
Dalian University of Technology · CNBeijing University of Technology · CNDalian Institute of Chemical Physics · CNHong Kong Science and Technology Parks Corporation · HKHuaian First People’s Hospital · CNSouthern University of Science and Technology · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FOXA1, a transcription factor involved in epigenetic reprogramming, is crucial for breast cancer progression. However, the mechanisms by which FOXA1 achieves its oncogenic functions remain elusive. Here, we demonstrate that the O-linked β-

Indexed as

Breast NeoplasmsChromatinBinding SitesEpigenomicsHepatocyte Nuclear Factor 3-alphaHumansMicrofilament ProteinsChromatinEPB41L3 protein, humanFOXA1 protein, humanHepatocyte Nuclear Factor 3-alphaMicrofilament Proteins

Identifiers

PMID37595040
PMCPMC10438466
OpenAlexW4385971300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.