Evidence map›Paper›PMID 37594586›Full record

ArticleJournal of fluorescence2024

Bio-based Carbon dots Loaded with 5-Fu: A Multifunctional drug Delivery System.

Baijian Feng, Na Li, Yongguang Bi, Fansheng Kong, Zhong Wang, Shaofan Tan

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Functionalized Carbon Dots With Intrinsic Wnt/International journal of nanomedicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Baijian FengSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong, China.
Na LiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong, China.
Yongguang BiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong, China. biyongguang2002@163.com.
Fansheng KongSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong, China.
Zhong WangYunfu Traditional Chinese Medicine Hospital, Yunfu, 527300, China.
Shaofan TanGuangdong Dongshenglin Pharmaceutical Co., Ltd, Guangzhou, 510006, China.

Funding

Guangdong MEPP Fund No. GDOE [2019]A27Heyuan City Science and Technology Plan Project No.2018014Project of Guangdong Provincial Department of Education-special projects in key areas No.2021ZDZX4013Project of Traditional Chinese Medicine Bureau of Guangdong Province No.20231422Science and Technology Planning Project of Guangdong Science and Technology Department No.KTP20200170Science and Technology Planning Project of Guangzhou Science and Technology Bureau No.202102080365Yunfu City Science and Technology Plan Project No.2020020101Zhongshan Social Welfare and basic research program No.2020B2005
6 · The paper itself

Abstract

In the present work, a simple and efficient stirring method was used to successfully synthesize a novel multifunctional carbon dots-drug delivery system AMP-CDs@5-Fu in the form of intertwined filaments. The results showed that AMP-CDs@5-Fu had the highest final release in the medium mimicking the physiological environment of the human small intestine compared to that of 5-Fu and that the drug release behaviors followed a zero-grade drug release within the first 3 h. The results also showed that AMP-CDs@5-Fu could be used to reduce the toxicity of 5-Fu while significantly improving the anticancer ability. In vitro hemolysis and anticancer assays showed that AMP-CDs@5-Fu could significantly improve the anticancer ability while decreasing the toxicity of 5-Fu, and the hemolysis rate of AMP-CDs@5-Fu was significantly lower than that of 5-Fu; their IC

Indexed as

CarbonDrug Delivery SystemsFluorouracilQuantum DotsAnimalsAntineoplastic AgentsCell Line, TumorCell SurvivalDrug CarriersDrug LiberationDrug Screening Assays, AntitumorHemolysisHumansMiceAntineoplastic AgentsCarbonDrug CarriersFluorouracilAnticancerCarbon dotsCell imagingDrug releaseFu

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.