Evidence map›Paper›PMID 37594092›Full record

ArticleCurrent pharmaceutical biotechnology2024

Acute Toxicity, Anti-diabetic, and Anti-cancerous Potential of Trillium Govanianum-conjugated Silver Nanoparticles in Balb/c Mice.

Nazia Gulzar, Saiqa Andleeb, Abida Raza, Shaukat Ali, Iram Liaqat, Sadaf Azad Raja, Nazish Mazhar Ali, Rida Khan, Uzma Azeem Awan

Abstract read
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Article in Current pharmaceutical biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Therapeutic effect ofRSC advances · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Nazia GulzarDepartment of Zoology, Microbial Biotechnology Laboratory, University of Azad Jammu and Kashmir, Muzaffarabad, 13100, Pakistan.
Saiqa AndleebDepartment of Zoology, Microbial Biotechnology Laboratory, University of Azad Jammu and Kashmir, Muzaffarabad, 13100, Pakistan.
Abida RazaPMAS-arid Agriculture University Rawalpindi, Pakistan.
Shaukat AliDepartment of Zoology, Government College University, Lahore, Pakistan.
Iram LiaqatDepartment of Zoology, Government College University, Lahore, Pakistan.
Sadaf Azad RajaBioscience Department, COMSATS University, Park Road, Chak Shahzad, Islamabad, 44000, Pakistan.
Nazish Mazhar AliDepartment of Zoology, Government College University, Lahore, Pakistan.
Rida KhanDepartment of Zoology, Microbial Biotechnology Laboratory, University of Azad Jammu and Kashmir, Muzaffarabad, 13100, Pakistan.
Uzma Azeem AwanDepartment of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan.
Government College University, Lahore · PKUniversity of Azad Jammu and Kashmir · PKCOMSATS University Islamabad · PKNational University of Medical Sciences · PKPir Mehr Ali Shah Arid Agriculture University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current study aimed to develop an economic plant-based therapeutic agent to improve the treatment strategies for diseases at the nano-scale because Cancer and Diabetes mellitus are major concerns in developing countries. Therefore,

methodsIn the current study synthesis of silver nanoparticles using

resultsIt was discovered that Balb/c mice did not show any major alterations during observation of acute oral toxicity when administered orally both TGaqu (1000 mg/kg) and TGAgNPs (1000 mg/kg), and results revealed that 1000 mg/kg is not lethal dose as did not find any abnormalities in epidermal and dermal layers when exposed to TGAgNPs.

conclusionBoth in vivo and

Indexed as

Hypoglycemic AgentsMetal NanoparticlesMice, Inbred BALB CSilverAnimalsAntineoplastic AgentsArtemiaDiabetes Mellitus, ExperimentalFemaleMaleMicePlant ExtractsToxicity Tests, AcuteAntineoplastic AgentsHypoglycemic AgentsPlant ExtractsSilveranti-cancerous activityanti-diabetic activityBalb/c mice.Histopathologysilver nanoparticlesTrillium govanianum

Identifiers

PMID37594092
OpenAlexW4385969650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.