Evidence map›Paper›PMID 37594010›Full record

ArticleThoracic cancer2023

Role of prognostic nutritional index in postoperative radiotherapy for non-small cell lung cancer.

Hyejo Ryu, Changhoon Song, Jae-Sung Kim, Jae Hyun Jeon, Sukki Cho, Kwhanmien Kim, Sanghoon Jheon, Se Hyun Kim, Yu Jung Kim, Jong Seok Lee

Abstract read
In one paragraph

Article in Thoracic cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Development and Validation of a Predictive Nomogram for Early Postoperative Recurrence in Non-Small Cell Lung Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hyejo RyuDepartment of Radiation Oncology, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0002-8933-9638
Changhoon SongDepartment of Radiation Oncology, Seoul National University Bundang Hospital, Seongnam, South Korea.ORCID 0000-0002-0714-8775
Jae-Sung KimDepartment of Radiation Oncology, Seoul National University Bundang Hospital, Seongnam, South Korea.
Jae Hyun JeonDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
Sukki ChoDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
Kwhanmien KimDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
Sanghoon JheonDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
Se Hyun KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.ORCID 0000-0002-2292-906X
Yu Jung KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Jong Seok LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic nutritional index (PNI) is known to be correlated with clinical outcomes in non-small cell lung cancer (NSCLC) patients. However, its role has not been studied in patients who have undergone postoperative radiotherapy (PORT). This study aimed to investigate the relationship between PNI and survival and recurrence in NSCLC patients with PORT.

methodsWe reviewed 97 stage I-III NSCLC patients who received PORT between January 2006 and December 2016 at our institution. We obtained PNI values for both pre-RT (within 1 month before PORT) and post-RT (within 2 months after PORT) by using serum albumin and lymphocyte count. A cutoff value for PNI was determined by the receiver operating characteristic curve (ROC). The median follow-up period was 52.8 months.

resultsThe ROC curve of post-RT PNI exhibited a higher area under the curve (AUC 0.68, cut-off: 47.1) than that of pre-RT PNI (AUC 0.55, cutoff: 50.3), so the group was divided into high post-RT PNI (> 47.1) and low post-RT PNI (

conclusionsPNI after PORT was significantly associated with survival. This finding suggests that PNI can be used as a prognostic marker.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsHumansNutrition AssessmentPrognosisRetrospective StudiesSurvival Rateadjuvant radiotherapynon-small cell lung cancerpostoperative radiotherapyprognostic nutritional index

Identifiers

PMID37594010
PMCPMC10542465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.