ArticleRadiation oncology (London, England)2023
Effectiveness of bladder filling control during online MR-guided adaptive radiotherapy for rectal cancer.
Article in Radiation oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Early Experience Comparing Reduced Planning Target Volume Margins Using Cone Beam Computed Tomography Scan Guided Online Adaptive Radiation Therapy to Nonadaptive, Traditional Margin Plans for Muscle-Invasive Bladder Cancer.Advances in radiation oncology · 2026Article
- A study on strategies to optimize bladder volume consistency in radiotherapy patients.European journal of medical research · 2025Article
- CBCT-based online adaptive radiotherapy of the bladder - geometrical and dosimetrical considerations compared to conventional IGRT.Radiation oncology (London, England) · 2025Article
- Dosimetric effects of bladder volume changes in MR-guided radiotherapy for cervical cancer.BMC cancer · 2025Article
- Qualitative and quantitative evaluation of the role of CBCT in rectal cancer radiotherapy.La Radiologia medica · 2025Review
- Assessing intra- and interfraction motion and its dosimetric impacts on cervical cancer adaptive radiotherapy based on 1.5T MR-Linac.Radiation oncology (London, England) · 2024Article
- Impact of contrast-enhanced CT in the dosimetry of SBRT for liver metastases treated with MR-Linac.Radiation oncology (London, England) · 2024Article
- Dose tracking assessment for magnetic resonance guided adaptive radiotherapy of rectal cancers.Radiation oncology (London, England) · 2024Article
- Evaluating contouring accuracy and dosimetry impact of current MRI-guided adaptive radiation therapy for brain metastases: a retrospective study.Journal of neuro-oncology · 2024Article
- Potential dosimetric error in the adaptive workflow of a 1.5 T MR-Linac from patient movement relative to immobilisation systems.Physical and engineering sciences in medicine · 2024Article
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8 authors.
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Abstract
backgroundMagnetic resonance-guided adaptive radiotherapy (MRgART) treatment sessions at MR-Linac are time-consuming and changes in organs at risk volumes can impact the treatment dosimetry. This study aims to evaluate the feasibility to control bladder filling during the rectum MRgART online session and its effectiveness on plan dosimetry.
methodsA total of 109 online adaptive sessions of 24 rectum cancer patients treated at Unity 1.5 T MR-Linac with a short course radiotherapy (25 Gy, 5 Gy × 5) for whom the adaptive plan was optimized and recalculated online based on the daily magnetic resonance imaging (MRI) were analysed. Patients were fitted with a bladder catheter to control bladder filling; the bladder is emptied and then partially filled with a known amount of saline at the beginning and end of the online session. A first MRI ([Formula: see text]) acquired at the beginning of the session was used for plan adaptation and the second ([Formula: see text]) was acquired while approving the adapted plan and rigidly registered with the first to ensure the appropriateness of the isodoses on the ongoing delivery treatment. For each fraction, the time interval between the two MRIs and potential bladder changes were assessed with independent metrics, and the impact on the plan dosimetry was evaluated by comparing target and organs at risk dose volume histogram cut-off points of the plan adapted on [Formula: see text] and recalculated on [Formula: see text].
resultsMedian bladder volume variations, DSC, and HD of 8.17%, 0.922, and 2.92 mm were registered within a median time of 38 min between [Formula: see text] and [Formula: see text]; dosimetric differences < 0.65% were registered for target coverage, and < 0.5% for bladder, small bowel and femoral heads constraints, with a p value > 0.05.
conclusionThe use of a bladder filling control procedure can help ensure the dosimetric accuracy of the online adapted treatment delivered.
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