Evidence map›Paper›PMID 37592331›Full record

ArticleChinese medicine2023

Yin/Yang associated differential responses to Psoralea corylifolia Linn. In rat models: an integrated metabolomics and transcriptomics study.

Ming-Liang Zhang, Xu Zhao, Wei-Xia Li, Xiao-Yan Wang, Ming Niu, Hui Zhang, Yu-Long Chen, De-Xin Kong, Yuan Gao, Yu-Ming Guo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. OAF Blocks SIAH1-Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Ming-Liang Zhang *Henan Province Engineering Laboratory for Clinical Evaluation Technology of Chinese Medicine, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Xu Zhao *Senior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Wei-Xia LiHenan Province Engineering Laboratory for Clinical Evaluation Technology of Chinese Medicine, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Xiao-Yan WangHenan Province Engineering Laboratory for Clinical Evaluation Technology of Chinese Medicine, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Ming NiuSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Hui ZhangHenan Province Engineering Laboratory for Clinical Evaluation Technology of Chinese Medicine, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Yu-Long ChenHenan University of Traditional Chinese Medicine, Zhengzhou, China.
De-Xin KongHenan Province Engineering Laboratory for Clinical Evaluation Technology of Chinese Medicine, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Yuan GaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yu-Ming GuoSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhao-Fang BaiSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Yan-Ling ZhaoCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China. zhaoyl2855@126.com.
Jin-Fa TangHenan Province Engineering Laboratory for Clinical Evaluation Technology of Chinese Medicine, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China. a0519@163.com.
Xiao-He XiaoSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing, China. pharmacy302xxh@126.com.
Chinese PLA General Hospital · CNHenan University of Traditional Chinese Medicine · CNFirst Affiliated Hospital of Henan University of Traditional Chinese Medicine · CNCapital Medical University · CNChinese People's Liberation Army · CN

Funding

National Natural Science Foundation of China 82173993National Natural Science Foundation of China 82204638National Natural Science Foundation of China 82230118National Natural Science Foundation of China U1904129
6 · The paper itself

Abstract

ethnopharmacological relevancePsoralea corylifolia Linn. (BGZ) is a commonly used traditional Chinese medicine (TCM) for the treatment of kidney-yang deficiency syndrome (Yang AIM OF THE STUDY: Liver injury caused by TCM is a rare but potentially serious adverse drug reaction, and the identification of predisposed individuals for drug-induced liver injury (DILI) remains challenging. The study aimed to investigate the differential responses to BGZ in Yang MATERIALS AND

methodsThe corresponding animal models of Yang

resultsThe level changes of liver organ index, alanine aminotransferase (ALT), and aspartate aminotransferase (AST), suggested that BGZ has liver-protective and liver-damaging effects on Yang

conclusionsYin

Indexed as

Liver injuryMetabolomicsPredisposed individualPsoraleae FructusTranscriptomics

Identifiers

PMID37592331
PMCPMC10433582
OpenAlexW4385950602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.