Evidence map›Paper›PMID 37592275›Full record

ArticleBMC musculoskeletal disorders2023

Could extended laminectomy effectively prevent spinal cord injury due to spinal shortening after 3-column osteotomy?

Yuyue Chen, Haozhi Yang, Ningling Xie, Shuang Zhang, Xiaobao Zou, Chenfu Deng, Binbin Wang, Hengrui Li, Xiangyang Ma

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Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors at 1 institution in 1 country.

Yuyue Chen *Department of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Haozhi Yang *Department of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Ningling Xie *Department of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Shuang Zhang *Department of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Xiaobao ZouDepartment of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Chenfu DengDepartment of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Binbin WangDepartment of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Hengrui LiDepartment of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
Xiangyang MaDepartment of Orthopedics, General Hospital of Southern Theatre Command, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China. maxy1001@126.com.
Third Affiliated Hospital of Southern Medical University · CN

Funding

National Natural Science Foundation of China 81672232
6 · The paper itself

Abstract

objectiveTo explore whether the laminectomy extension can effectively prevent spinal cord injury (SCI) due to spinal shortening after 3-column osteotomy in goat models.

methodsA total of twenty healthy goats were included and done with 3-column osteotomy of T13 and L1 under the somatosensory evoked potential (SSEP) monitoring. The samples were divided into two groups. The first group underwent regular laminectomy while the second group underwent an extended laminectomy with an extra 10 mm-lamina cranial to L2. The SSEP measured after 3-column osteotomy was set as the baseline, and the SSEP decreased by 50% from the baseline amplitude and/or delayed by 10% relative to the baseline peak latency was set as positive results, which indicated spinal cord injury. The vertebral column was gradually shortened until the SSEP monitoring just did not show a positive result. The height of the initial osteotomy gap (the distance from the lower endplate of T12 to the upper endplate of L2), the shortened distance (△H), the number of spinal cord angulated and the changed angle of the spinal cord (△α) were measured and recorded in each group. Neurological function was evaluated by the Tarlov scores on day 2 postoperatively.

resultsAll the goats except one of the first group due to changes in the SSEP during the osteotomy were included and analyzed. In the first group, the height of the initial osteotomy segment and the safe shortening distances were 61.6 ± 2.6 mm and 35.2 ± 2.6 mm, respectively; the spinal cord of 5 goats was angulated (46.4 ± 6.6

conclusionsAn additional resection of 10 mm-lamina cranial to L2 showed the satisfactory effect in alleviating SCI after 3-column osteotomy. Timely and appropriate extend laminectomy could be a promising therapeutic strategy for SCI attributable to facilitating spinal cord angulation rather than spinal cord kinking and increasing the safe shortening distance.

Indexed as

LaminectomySpinal Cord InjuriesAnimalsGoatsOsteotomySpine3-Column osteotomyLaminectomy extensionPreventionSpinal cord InjurySpinal shortening

Identifiers

PMID37592275
PMCPMC10436457
OpenAlexW4385950539

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