Evidence map›Paper›PMID 37592265›Full record

ArticleMicrobial cell factories2023

Fused expression of Sm1-Chit42 proteins for synergistic mycoparasitic response of Trichoderma afroharzianum on Botrytis cinerea.

Hongyi Liu, Shaoqing Wang, Bo Lang, Yaqian Li, Xinhua Wang, Jie Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial cell factories, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hongyi LiuSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Shaoqing WangSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Bo LangSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Yaqian LiSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Xinhua WangSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Jie ChenSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China. jiechen59@sjtu.edu.cn.
Shanghai Jiao Tong University · CN

Funding

Innovation Action Program of the Shanghai Science and Technology Commission No. 21N 41900200National Natural Science Foundation of China number 31872015
6 · The paper itself

Abstract

Sm1 and Chit42 of Trichoderma have been universally confirmed as crucial biocontrol factors against pathogen infection through induced resistance and mycoparasitism, respectively. However, not enough work has been conducted to understand the novel function of fused expression of these two proteins in Trichoderma. The results of this study demonstrated that Sm1-Chit42 protein (SCf) engineered T. afroharzianum strain OE:SCf exerted synergistic inhibition to Botrytis cinerea growth at multiple stages of mycoparasitic interaction of T. afroharzianum and B. cinerea including chemotropism sensing, hyphal coiling, hydrophobicity modulation, cell wall adhesion, virulence reduction and pathogen killing by ROS. These results highlight a novel mycoparasitic system in Trichoderma strains engineered with Sm1-Chit42 chimeric protein to combat B. cinerea growth and reproduction, which would lay a strong foundation for exploring a new engineered Trichoderma biofungicide created with chimeric proteins in the future.

Indexed as

HypocrealesTrichodermaBotrytisCell WallBotrytis cinereaChitin degradationHyphae recognitionMycoparasitismTrichoderma afroharzianum

Identifiers

PMID37592265
PMCPMC10433591
OpenAlexW4385951633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.