ArticleRespiratory research2023
Race-specific spirometry equations may overestimate asthma control in Black children and adolescents.
Article in Respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Factors Associated with Uninterpretable Spirometry During Asthma Screening in Children with Sickle Cell Disease: An Expanded Multicenter Study in French Guiana.Children (Basel, Switzerland) · 2026Article
- Removing race from pulmonary function tests in children with idiopathic scoliosis.Spine deformity · 2026Article
- Implications of removing race from spirometry reference equations in children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025Article
- Identifying and Addressing the Hidden Risks of Mild Asthma.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- Race-neutral versus race-specific GLI reference equations on spirometry interpretation in the general population.Scientific reports · 2025Article
- Comparison of Race-Neutral versus Race-Specific Spirometry Equations for Evaluation of Child Asthma.American journal of respiratory and critical care medicine · 2025Article
- Moving Away from Segregated Lung Function Equations: Effects of Transitioning to Race-Neutral References in Children.American journal of respiratory and critical care medicine · 2025Article
- Race-Specific and Race-Neutral Equations for Lung Function and Asthma Diagnosis in Black Children.JAMA network open · 2025Article
- Assessing the Impact of Different Spirometric Equations on Asthma Severity and Control Among Children in Jordan: A Retrospective Study.Pulmonary medicine · 2025Article
- How should trial teams make decisions about the proportions and diversity of the ethnic groups in their trial?Trials · 2024Article
- Rethinking the Role of Race in Lung Function: The Shift to Race-Neutral Spirometry Interpretation.Mayo Clinic proceedings · 2024Article
- Race-Neutral Equations and Pulmonary Function Test Interpretation in Two Pediatric Cohorts.The Journal of pediatrics · 2024Article
- Impact of CYP3A5 Polymorphisms on Pediatric Asthma Outcomes.International journal of molecular sciences · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundA growing body of evidence suggests that use of race terms in spirometry reference equations underestimates disease burden in Black populations, which may lead to disparities in pulmonary disease outcomes. Data on asthma-specific health consequences of using race-adjusted spirometry are lacking.
methodsWe performed a secondary analysis of 163 children from two observational asthma studies to determine the frequencies of participants with ppFEV1 < 80% (consistent with uncontrolled asthma) or ppFEV1 ≥ 80% using race-specific (GLI-African American or Caucasian) vs. race-neutral (GLI-Global) spirometry and their alignment with indicators of asthma control (Asthma Control Test™, ACT). Comparisons of mean ppFEV1 values were conducted using Wilcoxon matched-pairs signed-rank tests. Two group comparisons were conducted using Wilcoxon rank-sum tests.
resultsData from 163 children (100 Black, 63 White) were analyzed. Mean ppFEV
conclusionsUse of race-specific reference equations in Black children may increase the risk of inappropriately labeling asthma as controlled.
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Registered trials
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