Evidence map›Paper›PMID 37592210›Full record

ArticleBMC psychiatry2023

The effects of environmental factors associated with childhood urbanicity on brain structure and cognition.

Xiao Zhang, Hao Yan, Hao Yu, Yuyanan Zhang, Hao Yang Tan, Dai Zhang, Weihua Yue

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Xiao ZhangInstitute of Mental Health, National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, 51 Huayuanbei Road, Haidian District, Beijing, 100191, China. zhangx@bjmu.edu.cn.
Hao YanInstitute of Mental Health, National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, 51 Huayuanbei Road, Haidian District, Beijing, 100191, China.
Hao YuDepartment of Psychiatry, Jining Medical University, Jining, Shandong, China.
Yuyanan ZhangInstitute of Mental Health, National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, 51 Huayuanbei Road, Haidian District, Beijing, 100191, China.
Hao Yang TanLieber Institute for Brain Development, Baltimore, MD, 21205, US.
Dai ZhangInstitute of Mental Health, National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, 51 Huayuanbei Road, Haidian District, Beijing, 100191, China.
Weihua YueInstitute of Mental Health, National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, 51 Huayuanbei Road, Haidian District, Beijing, 100191, China. dryue@bjmu.edu.cn.
Peking University · CNPeking University Sixth Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNJining Medical University · CNJohns Hopkins University · US

Funding

Effects of genes and childhood environment on brain mechanisms of schizophrenia rR01MH101053 · NIMH · LIEBER INSTITUTE, INC. · PI TAN, HAO YANG · 2013 to 2015
$583k
NIMH NIH HHS R01 MH101053
6 · The paper itself

Abstract

Urbanization is a trend lasting for more than one century worldwide. Four hundred ninety male and female adult Chinese Han participants with different urban and rural childhoods were included in this study. Early-life urban environment was found benefit for total grey matter volume (GMV), dorsolateral prefrontal cortex (DLPFC) GMV, temporal pole (TP) GMV and cognition function, and negatively correlated with medial prefrontal cortex (MPFC) GMV. Regression analysis showed that maternal education was a protective factor for total and DLPFC GMVs, while having siblings was better for MPFC GMV. Total, DLPFC and TP GMVs acts mediation effects between childhood urbanicity and different cognitive domains. These findings may suggest some pros and cons on brain structure associated with childhood urbanicity and related environmental factors.

Indexed as

BrainCognitionAdultCerebral CortexChildFemaleGray MatterHumansMalePrefrontal CortexChildhood environmentCognitionGrey matter volumeHaving siblingsMaternal educationUrbanicity

Identifiers

PMID37592210
PMCPMC10433654
OpenAlexW4385954002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.