ArticleCommunications biology2023
ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice.
Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Role of Acid-Sensing Ion Channels 1a in the Regulation of Obesity and the Gut Microbiota.Obesity (Silver Spring, Md.) · 2026Article
- Acid-sensing ion channel 1a deficiency drives endocrine hypertension in male mice.The Journal of physiology · 2026Article
- The impact of Asic2 deletion on metabolic homeostasis in mice.Physiological reports · 2025Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
The body temperature of mice is higher at night than during the day. We show here that global deletion of acid-sensing ion channel 1a (ASIC1a) results in lower body temperature during a part of the night. ASICs are pH sensors that modulate neuronal activity. The deletion of ASIC1a decreased the voluntary activity at night of mice that had access to a running wheel but did not affect their spontaneous activity. Daily rhythms of thyrotropin-releasing hormone mRNA in the hypothalamus and of thyroid-stimulating hormone β mRNA in the pituitary, and of prolactin mRNA in the hypothalamus and pituitary were suppressed in ASIC1a
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Registered trials
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