ArticleNature plants2023
A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis.
Article in Nature plants, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How Useful Are Plant Traits in Explaining Variation in Phyllosphere Microbial Abundance and Composition Across Hosts?Environmental microbiology · 2025Pooled it
- Rational reduction of a sorghum SynCom that preserves growth promotion reveals flavonoid-mediated plant-microbe interactions.The New phytologist · 2026Article
- Review
- Multi-omics reveals the involvement of endophytes in the growth of Moso bamboo (Phyllostachys edulis) shoots.Communications biology · 2026Article
- The plant microbiota: From theoretical advances to applications.Fundamental research · 2026Review
- High nitrogen-induced changes in rhizosphere microbial community structure can modulate disease susceptibility to the rice blast.Environmental microbiome · 2026Article
- Wheat mycobiome dynamics driven by interseasonal crop-crop transfer and Fusarium head blight.Frontiers in microbiology · 2026Article
- Intercropping-mediated enrichment of core microbiome enhances suppression of Verticillium wilt in cotton.Environmental microbiome · 2025Article
- The Role of Phyllosphere Microbes and Viruses in Biocontrol of Pathogenic Fungi.Microbial biotechnology · 2025Review
- Toward a plant biotechnological application of phyllosphere bacteria.Plant biotechnology (Tokyo, Japan) · 2025Article
- Potential and challenges for application of microbiomes in agriculture.The Plant cell · 2025Review
- Variety-dependent seed endophytic bacteria enhance stress tolerance to and bioaccumulation of ciprofloxacin in choy sum (Brassica parachinensis).Microbiome · 2025Article
- Unveiling Microbial Dynamics: How Forest Aging Shapes the Microbial Communities ofEcology and evolution · 2025Article
- Plant exudates-driven microbiome recruitment and assembly facilitates plant health management.FEMS microbiology reviews · 2025Review
- Review
- Plant microbiota feedbacks through dose-responsive expression of general non-self response genes.Nature plants · 2025Article
- CEP signaling coordinates plant immunity with nitrogen status.Nature communications · 2024Article
- Plant Pattern recognition receptors: Exploring their evolution, diversification, and spatiotemporal regulation.Current opinion in plant biology · 2024Article
- Review
- MAPK Cascades in Plant Microbiota Structure and Functioning.Journal of microbiology (Seoul, Korea) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Although many studies have shown that microbes can ectopically stimulate or suppress plant immune responses, the fundamental question of whether the entire preexisting microbiota is indeed required for proper development of plant immune response remains unanswered. Using a recently developed peat-based gnotobiotic plant growth system, we found that Arabidopsis grown in the absence of a natural microbiota lacked age-dependent maturation of plant immune response and were defective in several aspects of pattern-triggered immunity. Axenic plants exhibited hypersusceptibility to infection by the bacterial pathogen Pseudomonas syringae pv. tomato DC3000 and the fungal pathogen Botrytis cinerea. Microbiota-mediated immunocompetence was suppressed by rich nutrient conditions, indicating a tripartite interaction between the host, microbiota and abiotic environment. A synthetic microbiota composed of 48 culturable bacterial strains from the leaf endosphere of healthy Arabidopsis plants was able to substantially restore immunocompetence similar to plants inoculated with a soil-derived community. In contrast, a 52-member dysbiotic synthetic leaf microbiota overstimulated the immune transcriptome. Together, these results provide evidence for a causal role of a eubiotic microbiota in gating proper immunocompetence and age-dependent immunity in plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.